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Gene Symbol:
HFE
Gene Name:
hemochromatosis
Gene Aliases:
HFE1, HH, HLA-H, MVCD7, TFQTL2
Chromosome Location:
Chr.6: 26087281 - 26096216 on Build GRCh38
UniGene ID:
Hs.233325
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID n349309

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Catalog # 4390771
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: HFE
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq XM_011514543.2 XP_011512845.1 7 2437
GenBank mRNA AF147392.1 - 1 143
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID Transcript Location
GenBankmRNA DA957218.1 - 1 171 Chr. 6 - 26095509 - 26096070 [+] on Build GRCh38
GenBankmRNA T59431.1 - 73 Chr. - - [-] on Build
GenBankmRNA BX107211.1 - 1 242 Chr. 6 - 26095471 - 26096083 [+] on Build GRCh38

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More Information


Gene Ontology Categories:

Function(s) Process(es)

antigen processing and presentation of peptide antigen via MHC class I
negative regulation of T cell antigen processing and presentation
negative regulation of T cell cytokine production
protein complex assembly
cellular iron ion homeostasis
acute-phase response
immune response
female pregnancy
response to iron ion
cellular response to iron ion starvation
positive regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
antigen processing and presentation
BMP signaling pathway
positive regulation of protein binding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
hormone biosynthetic process
positive regulation of receptor-mediated endocytosis
iron ion homeostasis
multicellular organismal iron ion homeostasis
cellular response to iron ion
positive regulation of peptide hormone secretion
liver regeneration
iron ion import into cell
negative regulation of receptor binding
positive regulation of receptor binding
positive regulation of ferrous iron import into cell
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
positive regulation of ferrous iron binding
positive regulation of transferrin receptor binding
response to iron ion starvation
regulation of protein localization to cell surface
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of receptor activity
positive regulation of receptor activity
negative regulation of CD8-positive, alpha-beta T cell activation
antigen binding
receptor binding
protein binding
beta-2-microglobulin binding
co-receptor binding
peptide antigen binding
transferrin receptor binding

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