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Gene Symbol:
PTPN1
Gene Name:
protein tyrosine phosphatase, non-receptor type 1
Gene Aliases:
PTP1B
Chromosome Location:
Chr.20: 50510321 - 50584762 on Build GRCh38
UniGene ID:
Hs.417549
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID VHS41291
Size 20 nmol
Availability Made To Order
Catalog # 1299001
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PTPN1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001278618.1 NP_001265547.1 6 839
NM_002827.3 NP_002818.1 7 930
GenBank mRNA AK290638.1 - 7 897
AK299830.1 - 6 777
AK316563.1 - 7 872
BC015660.2 - 7 859 4844022
BC018164.1 - 7 840 4338750
BT006752.1 - 7 723
M31724.1 - 7 813
M33689.1 - 7 795

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More Information


Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Function(s) Process(es)

protein dephosphorylation
activation of signaling protein activity involved in unfolded protein response
activation of JUN kinase activity
insulin receptor signaling pathway
regulation of signal transduction
negative regulation of signal transduction
regulation of endocytosis
negative regulation of vascular endothelial growth factor receptor signaling pathway
endoplasmic reticulum unfolded protein response
actin cytoskeleton reorganization
regulation of intracellular protein transport
peptidyl-tyrosine dephosphorylation
platelet-derived growth factor receptor-beta signaling pathway
IRE1-mediated unfolded protein response
negative regulation of MAP kinase activity
negative regulation of insulin receptor signaling pathway
regulation of type I interferon-mediated signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway
positive regulation of protein tyrosine kinase activity
negative regulation of ERK1 and ERK2 cascade
cell-cell adhesion
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of IRE1-mediated unfolded protein response
negative regulation of PERK-mediated unfolded protein response
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
positive regulation of receptor catabolic process
protein tyrosine phosphatase activity
insulin receptor binding
protein binding
zinc ion binding
enzyme binding
protein kinase binding
receptor tyrosine kinase binding
poly(A) RNA binding
ephrin receptor binding
protein phosphatase 2A binding
cadherin binding involved in cell-cell adhesion

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