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Gene Symbol:
EIF2AK2
Gene Name:
eukaryotic translation initiation factor 2 alpha kinase 2
Gene Aliases:
EIF2AK1, PKR, PPP1R83, PRKR
Chromosome Location:
Chr.2: 37099210 - 37157065 on Build GRCh38
UniGene ID:
Hs.131431
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID HSS183403
Size 20 nmol
Availability Made To Order
Catalog # 1299001
Price
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: EIF2AK2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001135651.2 NP_001129123.1 10 1064
NM_001135652.2 NP_001129124.1 8 757
NM_002759.3 NP_002750.1 10 1298
XM_011532987.2 XP_011531289.1 10 998
XM_017004503.1 XP_016859992.1 10 994
GenBank mRNA AK290655.1 - 10 984
AK313818.1 - 9 821
AY302136.1 - 8 741
BC007769.2 - 9 840
BC022314.1 - 10 952
BC040851.1 - 10 1064
BC057805.1 - 10 969
BC093676.1 - 8 769 7939521
BC101475.1 - 8 769 8068981
BC143228.1 - 8 768
BC143230.1 - 8 769 9051731
M35663.1 - 9 927
M85294.1 - 8 771

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More Information


Gene Ontology Categories:

Function(s) Process(es)

activation of MAPKK activity
positive regulation of cytokine production
transcription, DNA-templated
translation
protein phosphorylation
negative regulation of cell proliferation
response to mechanical stimulus
response to virus
response to toxic substance
regulation of translational initiation by eIF2 alpha phosphorylation
negative regulation of translation
peptidyl-tyrosine phosphorylation
evasion or tolerance by virus of host immune response
endoplasmic reticulum unfolded protein response
response to lipopolysaccharide
positive regulation of chemokine production
positive regulation of stress-activated MAPK cascade
response to vitamin E
negative regulation of osteoblast proliferation
regulation of protein phosphatase type 2A activity
cellular response to amino acid starvation
response to interferon-alpha
positive regulation of apoptotic process
negative regulation of apoptotic process
response to exogenous dsRNA
negative regulation of viral genome replication
innate immune response
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
defense response to virus
regulation of NLRP3 inflammasome complex assembly
positive regulation of NIK/NF-kappaB signaling
regulation of hematopoietic progenitor cell differentiation
regulation of hematopoietic stem cell proliferation
regulation of hematopoietic stem cell differentiation
double-stranded RNA binding
protein kinase activity
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
protein phosphatase type 2A regulator activity
poly(A) RNA binding

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