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Gene Symbol:
ERN1
Gene Name:
endoplasmic reticulum to nucleus signaling 1
Gene Aliases:
IRE1, IRE1P, IRE1a, hIRE1p
Chromosome Location:
Chr.17: 64039142 - 64130819 on Build GRCh38
UniGene ID:
Hs.133982
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID HSS176615
Size 20 nmol
Availability Made To Order
Catalog # 1299001
Price
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: ERN1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001433.3 NP_001424.3 20, 21 2776
XM_017024347.1 XP_016879836.1 20, 21 4130
XM_017024348.1 XP_016879837.1 19, 20 4028
GenBank mRNA AB209869.1 - 20, 21 2759
AF059198.1 - 20, 21 2759
AK292403.1 - 20, 21 2802
BC130405.1 - 20, 21 2709 40146436
BC130407.1 - 20, 21 2709 40146438

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More Information


Gene Ontology Categories:

Function(s) Process(es)

endothelial cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA cleavage
mRNA catabolic process
protein phosphorylation
activation of signaling protein activity involved in unfolded protein response
cell cycle arrest
activation of JUN kinase activity
regulation of macroautophagy
positive regulation of RNA splicing
response to endoplasmic reticulum stress
cellular response to vascular endothelial growth factor stimulus
peptidyl-serine autophosphorylation
IRE1-mediated unfolded protein response
protein autophosphorylation
mRNA splicing, via endonucleolytic cleavage and ligation
mRNA endonucleolytic cleavage involved in unfolded protein response
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to glucose stimulus
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of endoplasmic reticulum unfolded protein response
insulin metabolic process
peptidyl-serine trans-autophosphorylation
magnesium ion binding
endoribonuclease activity
protein serine/threonine kinase activity
protein binding
ATP binding
enzyme binding
Hsp70 protein binding
identical protein binding
protein homodimerization activity
ADP binding
Hsp90 protein binding

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