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Gene Symbol:
HFE
Gene Name:
hemochromatosis
Gene Aliases:
HFE1, HH, HLA-H, MVCD7, TFQTL2
Chromosome Location:
Chr.6: 26087281 - 26096216 on Build GRCh38
UniGene ID:
Hs.233325
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID HSS166968
Size 20 nmol
Availability Made To Order
Catalog # 1299001
Price
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: HFE
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000410.3 NP_000401.1 5 1118
NM_001300749.1 NP_001287678.1 5 1118
NM_139003.2 NP_620572.1 4 800
NM_139004.2 NP_620573.1 4 842
NM_139006.2 NP_620575.1 5 1076
NM_139007.2 NP_620576.1 4 854
NM_139008.2 NP_620577.1 4 812
NM_139009.2 NP_620578.1 5 1049
NM_139010.2 NP_620579.1 3 578
NM_139011.2 NP_620580.1 2 302
XM_011514543.2 XP_011512845.1 5 1080
GenBank mRNA AF079407.1 - 5 952
AF079408.1 - 4 730
AF079409.1 - 4 688
AF115265.1 - 5 969
AF144242.1 - 4 805
AF149804.1 - 4 684
AJ249335.1 - 5 1049
AJ249336.1 - 4 854
AJ249337.1 - 4 842
AJ249338.1 - 2 302
AJ250635.1 - 3 578
AK300933.1 - 5 962
AY205604.1 - 4 719
BC074721.2 - 6 998 30915171
BC117201.1 - 5 993 40125752
BC117203.1 - 5 993 40125754
JN375755.1 - 2 176
JN375756.1 - 2 175
JN375757.1 - 2 166
JN375758.1 - 2 175
JN375759.1 - 2 181
U60319.1 - 5 1179

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More Information


Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Function(s) Process(es)

antigen processing and presentation of peptide antigen via MHC class I
negative regulation of T cell antigen processing and presentation
negative regulation of T cell cytokine production
protein complex assembly
cellular iron ion homeostasis
acute-phase response
immune response
female pregnancy
response to iron ion
cellular response to iron ion starvation
positive regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
antigen processing and presentation
BMP signaling pathway
positive regulation of protein binding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
hormone biosynthetic process
positive regulation of receptor-mediated endocytosis
iron ion homeostasis
multicellular organismal iron ion homeostasis
cellular response to iron ion
positive regulation of peptide hormone secretion
liver regeneration
iron ion import into cell
negative regulation of receptor binding
positive regulation of receptor binding
positive regulation of ferrous iron import into cell
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
positive regulation of ferrous iron binding
positive regulation of transferrin receptor binding
response to iron ion starvation
regulation of protein localization to cell surface
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of receptor activity
positive regulation of receptor activity
negative regulation of CD8-positive, alpha-beta T cell activation
antigen binding
receptor binding
protein binding
beta-2-microglobulin binding
co-receptor binding
peptide antigen binding
transferrin receptor binding

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