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Gene Symbol:
IKBKB
Gene Name:
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene Aliases:
IKK-beta, IKK2, IKKB, IMD15, NFKBIKB
Chromosome Location:
Chr.8: 42271302 - 42332653 on Build GRCh38
UniGene ID:
Hs.597664
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID HSS105292
Size 20 nmol
Availability Made To Order
Catalog # 1299001
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: IKBKB
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001190720.2 NP_001177649.1 12, 13 1431
NM_001242778.1 NP_001229707.1 12, 13 1459
NM_001556.2 NP_001547.1 13, 14 1554
NR_033818.1 13, 14 1610
NR_033819.1 13, 14 1554
NR_040009.1 13, 14 1501
XM_005273490.2 XP_005273547.1 13, 14 1554
XM_005273491.4 XP_005273548.1 12, 13 1454
XM_005273492.3 XP_005273549.1 13, 14 1554
XM_005273493.3 XP_005273550.1 10, 11 1250
XM_005273494.2 XP_005273551.1 13, 14 1554
XM_005273495.2 XP_005273552.1 12, 13 1295
XM_005273496.3 XP_005273553.1 11, 12 1315
XM_005273498.3 XP_005273555.1 9, 10 1124
XM_011544517.2 XP_011542819.1 13, 14 1552
XM_011544518.2 XP_011542820.1 12, 13 1404
XM_011544519.2 XP_011542821.1 12, 13 1422
XM_011544520.2 XP_011542822.1 10, 11 1269
XM_011544521.2 XP_011542823.1 11, 12 1382
XM_011544522.2 XP_011542824.1 10, 11 1230
XM_017013396.1 XP_016868885.1 12, 13 1507
GenBank mRNA AB209090.1 - 12, 13 1372
AF029684.1 - 12, 13 1368
AF031416.1 - 12, 13 1368
AF080158.1 - 13, 14 1511
AK091297.1 - 7, 8 950
AK290952.1 - 13, 14 1420
AK298241.1 - 10, 11 1118
AK302723.1 - 12, 13 1415
AK303294.1 - 12, 13 1443
AK303528.1 - 12, 13 1447
AK316418.1 - 12, 13 1415
BC144080.1 - 12, 13 1345
BX648165.1 - 12, 13 2006

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More Information


Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase protein modifying enzyme

Gene Ontology Categories:

Function(s) Process(es)

stimulatory C-type lectin receptor signaling pathway
skeletal muscle contraction
protein phosphorylation
inflammatory response
I-kappaB kinase/NF-kappaB signaling
I-kappaB phosphorylation
positive regulation of cell proliferation
response to virus
response to toxic substance
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of neuron projection development
cortical actin cytoskeleton organization
neuron projection development
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
negative regulation of myosin-light-chain-phosphatase activity
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
regulation of phosphorylation
response to drug
serine phosphorylation of STAT protein
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
stress-activated MAPK cascade
nucleotide-binding oligomerization domain containing signaling pathway
interleukin-1-mediated signaling pathway
response to fatty acid
cellular response to tumor necrosis factor
establishment of protein localization to plasma membrane
positive regulation of neuron death
regulation of establishment of endothelial barrier
negative regulation of bicellular tight junction assembly
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
protein kinase binding
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding

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