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Gene Symbol:
HMGCR
Gene Name:
3-hydroxy-3-methylglutaryl-CoA reductase
Gene Aliases:
LDLCQ3
Chromosome Location:
Chr.5: 75336334 - 75362101 on Build GRCh38
UniGene ID:
Hs.628096
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID HSS104864
Size 20 nmol
Availability Made To Order
Catalog # 1299001
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: HMGCR
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000859.2 NP_000850.1 19 2626
NM_001130996.1 NP_001124468.1 18 2467
XM_011543357.1 XP_011541659.1 19 2777
XM_011543358.1 XP_011541660.1 19 2664
XM_011543359.1 XP_011541661.1 18 2618
GenBank mRNA AK292892.1 - 19 2557
AK296499.1 - 19 2781
AK299655.1 - 6 705
AK312437.1 - 18 2470
AY429543.1 - 3 300
BC033692.1 - 18 2403 5212903
M11058.1 - 19 2520

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008255, M62766, BC059873, AK079302, AK159899, and others.

Gene Ontology Categories:

Function(s) Process(es)

cholesterol biosynthetic process
ubiquinone metabolic process
aging
response to nutrient
isoprenoid biosynthetic process
visual learning
negative regulation of striated muscle cell apoptotic process
positive regulation of cardiac muscle cell apoptotic process
coenzyme A metabolic process
positive regulation of stress-activated MAPK cascade
negative regulation of MAP kinase activity
myoblast differentiation
response to ethanol
negative regulation of vasodilation
positive regulation of skeletal muscle tissue development
positive regulation of smooth muscle cell proliferation
protein tetramerization
oxidation-reduction process
negative regulation of wound healing
negative regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of ERK1 and ERK2 cascade
hydroxymethylglutaryl-CoA reductase (NADPH) activity
protein binding
hydroxymethylglutaryl-CoA reductase activity
protein homodimerization activity
coenzyme binding
protein phosphatase 2A binding
NADPH binding

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