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Gene Symbol:
Nlrp3
Gene Name:
NLR family, pyrin domain containing 3
Gene Aliases:
AGTAVPRL, AII/AVP, Cias1, FCAS, FCU, MWS, Mmig1, NALP3, Pypaf1
Chromosome Location:
Chr.11: 59541569 - 59566956 on Build GRCm38
UniGene ID:
Mm.54174
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 90320

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Nlrp3
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_145827.3 NP_665826.1 4 1939
GenBank mRNA AF486632.1 - 5 1835
AY337285.1 - 3 1725
AY355340.1 - 3 1713
AY495376.1 - 4 1939
AY495377.1 - 5 1835
BC116174.1 - 4 1899 40048724
BC116175.1 - 4 1899 40048725
KF032621.1 - 3 1715

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001191642, XM_006246457, XM_006246458, XM_006246453, XM_006246455.

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of acute inflammatory response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
negative regulation of NF-kappaB transcription factor activity
interleukin-1 beta production
interleukin-18 production
negative regulation of NF-kappaB import into nucleus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
NLRP3 inflammasome complex assembly
interleukin-1 secretion
negative regulation of interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
regulation of inflammatory response
negative regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
defense response to virus
cellular response to lipopolysaccharide
nucleotide binding
protein binding
ATP binding

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