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Gene Symbol:
Irak3
Gene Name:
interleukin-1 receptor-associated kinase 3
Gene Aliases:
4833428C18Rik, AI563835, IRAK-M
Chromosome Location:
Chr.10: 120141648 - 120201597 on Build GRCm38
UniGene ID:
Mm.146194
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 83052

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Irak3
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_028679.3 NP_082955.2 5 606
GenBank mRNA AF461763.1 - 5 586
AJ440757.2 - 5 528
AK014783.1 - 5 657
AK028436.1 - 519
AK029057.1 - 5 607
AK049210.1 - 5 637
BC120829.1 - 5 567 40129752
BC120831.1 - 5 567 40129754
BC144835.1 - 5 567

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108101, BC166731.

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of cytokine-mediated signaling pathway
toll-like receptor signaling pathway
protein phosphorylation
apoptotic process
signal transduction
response to virus
positive regulation of macrophage tolerance induction
negative regulation of macrophage cytokine production
phosphorylation
cytokine-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
response to peptidoglycan
response to lipopolysaccharide
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
negative regulation of protein catabolic process
regulation of apoptotic process
negative regulation of protein complex disassembly
regulation of protein complex disassembly
response to exogenous dsRNA
negative regulation of MAP kinase activity
negative regulation of innate immune response
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
interleukin-1-mediated signaling pathway
response to interleukin-1
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein homodimerization activity
protein heterodimerization activity

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