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Gene Symbol:
Ptpn11
Gene Name:
protein tyrosine phosphatase, non-receptor type 11
Gene Aliases:
2700084A17Rik, AW536184, PTP1D, PTP2C, SAP-2, SH-PTP2, SH-PTP3, SHP-2, Shp2, Syp
Chromosome Location:
Chr.5: 121130533 - 121191397 on Build GRCm38
UniGene ID:
Mm.8681
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 68983

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Ptpn11
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001109992.1 NP_001103462.1 7 992
NM_011202.3 NP_035332.1 7 992
GenBank mRNA AK147354.1 - 7 963
AK159501.1 - 7 992
AK159587.1 - 7 992
AK163809.1 - 4 420
BC057398.1 - 7 924 6409640
BC059278.1 - 7 970 2866038
D84372.1 - 7 868

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001177593, NM_013088, D83016, U05963, U09307.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Function(s) Process(es)

DNA damage checkpoint
activation of MAPK activity
protein dephosphorylation
lipid metabolic process
triglyceride metabolic process
epidermal growth factor receptor signaling pathway
integrin-mediated signaling pathway
axonogenesis
brain development
heart development
hormone-mediated signaling pathway
positive regulation of signal transduction
dephosphorylation
platelet formation
microvillus organization
abortive mitotic cell cycle
regulation of cell adhesion mediated by integrin
negative regulation of cell adhesion mediated by integrin
multicellular organism growth
organ growth
peptidyl-tyrosine dephosphorylation
megakaryocyte development
atrioventricular canal development
ERBB signaling pathway
regulation of multicellular organism growth
hormone metabolic process
glucose homeostasis
positive regulation of mitotic cell cycle
negative regulation of insulin secretion
regulation of protein export from nucleus
positive regulation of hormone secretion
negative regulation of hormone secretion
platelet-derived growth factor receptor signaling pathway
neurotrophin TRK receptor signaling pathway
ephrin receptor signaling pathway
multicellular organismal reproductive process
genitalia development
inner ear development
homeostasis of number of cells within a tissue
negative regulation of cortisol secretion
negative regulation of growth hormone secretion
face morphogenesis
intestinal epithelial cell migration
positive regulation of ERK1 and ERK2 cascade
positive regulation of glucose import in response to insulin stimulus
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
SH3/SH2 adaptor activity
insulin receptor binding
protein binding
hydrolase activity
phosphatase activity
protein domain specific binding
receptor tyrosine kinase binding
D1 dopamine receptor binding
phospholipase binding
insulin receptor substrate binding
peptide hormone receptor binding

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