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Gene Symbol:
Ptpn1
Gene Name:
protein tyrosine phosphatase, non-receptor type 1
Gene Aliases:
PTP-1B, PTP-HA2, PTP1B
Chromosome Location:
Chr.2: 167932303 - 167979385 on Build GRCm38
UniGene ID:
Mm.277916
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 68792

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Ptpn1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_011201.3 NP_035331.3 3 358
GenBank mRNA AK149979.1 - 3 314
AK150322.1 - 3 314
AK151371.1 - 3 271
AK153088.1 - 3 297
AK156281.1 - 3 319
AK157431.1 - 3 359
AK165949.1 - 4 438
AK166020.1 - 3 314
AK168255.1 - 3 296
AK168772.1 - 3 313
AK170620.1 - 3 314
AK171380.1 - 3 314
AK172206.1 - 4 431
AK185938.1 - 2 65
BC010191.1 - 3 276 3156854
M97590.1 - 3 274

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012637, XM_006235638, XM_006235639, BC081829, M33962.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Function(s) Process(es)

protein dephosphorylation
activation of JUN kinase activity
insulin receptor signaling pathway
regulation of signal transduction
dephosphorylation
regulation of endocytosis
negative regulation of vascular endothelial growth factor receptor signaling pathway
endoplasmic reticulum unfolded protein response
actin cytoskeleton reorganization
regulation of intracellular protein transport
response to endoplasmic reticulum stress
peptidyl-tyrosine dephosphorylation
platelet-derived growth factor receptor-beta signaling pathway
IRE1-mediated unfolded protein response
negative regulation of MAP kinase activity
regulation of insulin receptor signaling pathway
positive regulation of protein tyrosine kinase activity
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of PERK-mediated unfolded protein response
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
positive regulation of receptor catabolic process
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
insulin receptor binding
zinc ion binding
hydrolase activity
phosphatase activity
enzyme binding
protein kinase binding
receptor tyrosine kinase binding
poly(A) RNA binding
ephrin receptor binding
protein phosphatase 2A binding

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