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Gene Symbol:
PTPN22
Gene Name:
protein tyrosine phosphatase, non-receptor type 22
Gene Aliases:
LYP, LYP1, LYP2, PEP, PTPN8
Chromosome Location:
Chr.1: 113813811 - 113871761 on Build GRCh38
UniGene ID:
Hs.535276
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 5827

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PTPN22
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001193431.2 NP_001180360.1 13 1413
NM_001308297.1 NP_001295226.1 12 1341
NM_012411.5 NP_036543.4 11 1248
NM_015967.6 NP_057051.3 13 1413
XM_011541221.1 XP_011539523.1 12 1316
XM_011541222.1 XP_011539524.1 13 1394
XM_011541223.2 XP_011539525.1 13 1394
XM_011541225.2 XP_011539527.1 12 1343
XM_017001004.1 XP_016856493.1 13 1394
XM_017001005.1 XP_016856494.1 13 1375
GenBank mRNA AF001846.1 - 13 1321
AF077031.1 - 13 1349
AK303124.1 - 9 1048
AK310570.1 - 8 985
AK310698.1 - 13 1366
BC071670.1 - 11 1187 5497108
GU479452.1 - 13 1327
JN084012.1 - 12 1218

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More Information


Gene Ontology Categories:

Function(s) Process(es)

protein dephosphorylation
autophagy
negative regulation of autophagy
positive regulation of gene expression
negative regulation of gene expression
T cell differentiation
lipopolysaccharide-mediated signaling pathway
positive regulation of type I interferon production
response to lipopolysaccharide
negative regulation of tumor necrosis factor production
regulation of natural killer cell proliferation
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
peptidyl-tyrosine dephosphorylation
phosphoanandamide dephosphorylation
negative regulation of JUN kinase activity
regulation of innate immune response
regulation of B cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
negative regulation of T cell activation
positive regulation of ERK1 and ERK2 cascade
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
cellular response to muramyl dipeptide
negative regulation of interleukin-6 secretion
regulation of NIK/NF-kappaB signaling
positive regulation of protein K63-linked ubiquitination
positive regulation of interferon-gamma secretion
negative regulation of p38MAPK cascade
negative regulation of interleukin-8 secretion
protein tyrosine phosphatase activity
protein binding
phosphatase activity
SH3 domain binding
kinase binding
ubiquitin protein ligase binding

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