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Gene Symbol:
PTPN2
Gene Name:
protein tyrosine phosphatase, non-receptor type 2
Gene Aliases:
PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP
Chromosome Location:
Chr.18: 12785478 - 12884351 on Build GRCh38
UniGene ID:
Hs.654527
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 4445

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PTPN2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001207013.1 NP_001193942.1 8 1094
NM_001308287.1 NP_001295216.1 6 920
NM_002828.3 NP_002819.2 7 1025
NM_080422.2 NP_536347.1 7 1025
NM_080423.2 NP_536348.1 7 1025
XM_005258124.3 XP_005258181.1 8 1092
XM_005258125.3 XP_005258182.1 8 1092
XM_011525705.2 XP_011524007.1 9 1312
XM_011525706.2 XP_011524008.1 6 813
XM_011525707.2 XP_011524009.1 3 420
XM_017025884.1 XP_016881373.1 7 1041
XM_017025885.1 XP_016881374.1 8 1227
XM_017025886.1 XP_016881375.1 6 915
XM_017025887.1 XP_016881376.1 6 866
XM_017025888.1 XP_016881377.1 6 866
GenBank mRNA AB209569.1 - 6 952
AK225706.1 - 8 973
AK290649.1 - 7 907
AK292570.1 - 7 925
BC008244.1 - 7 868 3872164
BC016727.1 - 7 937 4081330
M25393.1 - 7 891

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More Information


Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of cell proliferation
insulin receptor signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of lipid storage
B cell differentiation
T cell differentiation
erythrocyte differentiation
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of tyrosine phosphorylation of Stat6 protein
glucose homeostasis
negative regulation of macrophage differentiation
positive regulation of gluconeogenesis
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
negative regulation of T cell receptor signaling pathway
negative regulation of chemotaxis
regulation of interferon-gamma-mediated signaling pathway
negative regulation of interferon-gamma-mediated signaling pathway
negative regulation of type I interferon-mediated signaling pathway
negative regulation of protein tyrosine kinase activity
negative regulation of interleukin-6-mediated signaling pathway
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of interleukin-2-mediated signaling pathway
negative regulation of prolactin signaling pathway
negative regulation of interleukin-4-mediated signaling pathway
negative regulation of macrophage colony-stimulating factor signaling pathway
negative regulation of positive thymic T cell selection
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
negative regulation of platelet-derived growth factor receptor-beta signaling pathway
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
integrin binding
protein binding
protein kinase binding
syntaxin binding
receptor tyrosine kinase binding

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