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See other TP53 SIRNA Assays ›
Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 2714

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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: TP53
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000546.5 NP_000537.3 11 2073
NM_001126112.2 NP_001119584.1 11 2070
NM_001126113.2 NP_001119585.1 12 2133
NM_001126114.2 NP_001119586.1 12 2206
NM_001126115.1 NP_001119587.1 7 1753
NM_001126116.1 NP_001119588.1 8 1886
NM_001126117.1 NP_001119589.1 8 1813
NM_001126118.1 NP_001119590.1 10 2190
NM_001276695.1 NP_001263624.1 12 2133
NM_001276696.1 NP_001263625.1 12 2206
NM_001276697.1 NP_001263626.1 7 1753
NM_001276698.1 NP_001263627.1 8 1886
NM_001276699.1 NP_001263628.1 8 1813
NM_001276760.1 NP_001263689.1 11 2073
NM_001276761.1 NP_001263690.1 11 2070
GenBank mRNA AB082923.1 - 11 1934
AF052180.1 - 1 705
AF307851.1 - 11 2006
AK223026.1 - 5 1166
BC003596.1 - 11 1991 3544714
DQ186648.1 - 12 2144
DQ186649.1 - 12 2071
DQ186650.1 - 7 1757
DQ186651.1 - 8 1890
DQ186652.1 - 8 1817
DQ191317.1 - 11 2068
DQ286964.1 - 11 2013
FJ207420.1 - 11 2014
JN214348.1 - 10 1916
JN900492.1 - 10 2179
X01405.1 - 8 1572

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More Information


Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding

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