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See other APP SIRNA Assays ›
Gene Symbol:
APP
Gene Name:
amyloid beta precursor protein
Gene Aliases:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Chromosome Location:
Chr.21: 25880550 - 26171128 on Build GRCh38
UniGene ID:
Hs.434980
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 2530

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: APP
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000484.3 NP_000475.1 2 380
NM_001136016.3 NP_001129488.1 2 361
NM_001136131.2 NP_001129603.1 2 267
NM_001204301.1 NP_001191230.1 2 380
NM_001204302.1 NP_001191231.1 2 380
NM_001204303.1 NP_001191232.1 2 380
NM_201413.2 NP_958816.1 2 380
NM_201414.2 NP_958817.1 2 380
GenBank mRNA A02759.1 - 2 326
AK295621.1 - 2 322
AK296229.1 - 2 267
AK297229.1 - 2 244
AK297412.1 - 2 328
AK298861.1 - 282
AK311717.1 - 2 440
AK312326.1 - 2 245
BC004369.1 - 2 306
BC065529.1 - 2 311 6152423
BI559391.1 - 2 385
BM172428.1 - 2 380
X06989.1 - 2 304
Y00264.1 - 2 327

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019288, XM_006248010, XM_006248009, XM_006248011, XM_006248008, and others.
This siRNA also targets the following transcripts in Mouse: NM_001198826, NM_001198824, NM_001198823, NM_001198825, NM_007471, and others.

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Function(s) Process(es)

response to yeast
suckling behavior
platelet degranulation
mRNA polyadenylation
regulation of translation
protein phosphorylation
cellular copper ion homeostasis
endocytosis
response to oxidative stress
cell adhesion
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
axonogenesis
mating behavior
locomotory behavior
axo-dendritic transport
cholesterol metabolic process
adult locomotory behavior
visual learning
cellular process
response to lead ion
negative regulation of endopeptidase activity
positive regulation of peptidase activity
positive regulation of G2/M transition of mitotic cell cycle
axon midline choice point recognition
neuron remodeling
dendrite development
antibacterial humoral response
antifungal humoral response
extracellular matrix organization
forebrain development
neuron projection development
ionotropic glutamate receptor signaling pathway
regulation of multicellular organism growth
regulation of protein binding
cellular protein metabolic process
innate immune response
negative regulation of neuron differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
collateral sprouting in absence of injury
regulation of synapse structure or activity
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
neuromuscular process controlling balance
synaptic growth at neuromuscular junction
neuron apoptotic process
smooth endoplasmic reticulum calcium ion homeostasis
cellular response to cAMP
cellular response to norepinephrine stimulus
amyloid fibril formation
cellular response to nerve growth factor stimulus
DNA binding
serine-type endopeptidase inhibitor activity
receptor binding
protein binding
heparin binding
peptidase activator activity
enzyme binding
identical protein binding
transition metal ion binding
PTB domain binding
growth factor receptor binding

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