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Gene Symbol:
EZH2
Gene Name:
enhancer of zeste 2 polycomb repressive complex 2 subunit
Gene Aliases:
ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2
Chromosome Location:
Chr.7: 148807372 - 148884662 on Build GRCh38
UniGene ID:
Hs.444082
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 214021

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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: EZH2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001203247.1 NP_001190176.1 20 2391
NM_001203248.1 NP_001190177.1 20 2364
NM_001203249.1 NP_001190178.1 19 2365
NM_004456.4 NP_004447.2 20 2406
NM_152998.2 NP_694543.1 19 2274
XM_005249962.4 XP_005250019.1 20 4832
XM_005249963.4 XP_005250020.1 20 4805
XM_005249964.4 XP_005250021.1 19 4680
XM_011515883.2 XP_011514185.1 21 2381
XM_011515884.2 XP_011514186.1 20 2513
XM_011515885.2 XP_011514187.1 20 4822
XM_011515886.2 XP_011514188.1 21 2530
XM_011515887.2 XP_011514189.1 20 2379
XM_011515888.2 XP_011514190.1 20 2501
XM_011515889.2 XP_011514191.1 20 2303
XM_011515890.2 XP_011514192.1 19 4732
XM_011515891.2 XP_011514193.1 18 2466
XM_011515892.2 XP_011514194.1 19 4724
XM_011515893.2 XP_011514195.1 19 4715
XM_011515894.2 XP_011514196.1 19 2231
XM_011515895.2 XP_011514197.1 19 4705
XM_011515896.2 XP_011514198.1 18 4590
XM_011515897.2 XP_011514199.1 21 2557
XM_011515898.2 XP_011514200.1 21 2484
XM_017011817.1 XP_016867306.1 20 4848
XM_017011818.1 XP_016867307.1 21 2515
XM_017011819.1 XP_016867308.1 19 4707
XM_017011820.1 XP_016867309.1 19 2262
XM_017011821.1 XP_016867310.1 21 2542
GenBank mRNA AB208895.1 - 19 3335
AK092676.1 - 19 2173
AK293239.1 - 20 2302
AK302216.1 - 19 2365
AK314291.1 - 19 2216
BC010858.2 - 20 2335 3901250
BU953788.1 - 3 187
JF327843.1 - 17 1955
U61145.1 - 20 2287
X95653.1 - 20 2255

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001134979, XM_006236404, XM_006236408, XM_006236403, XM_006236405, and others.
This siRNA also targets the following transcripts in Mouse: NM_007971, NM_001146689, BC016391, BC003772, U52951, and others.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
chromatin organization
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of epithelial to mesenchymal transition
regulation of gliogenesis
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
cerebellar cortex development
hippocampus development
response to estradiol
negative regulation of transcription elongation from RNA polymerase II promoter
regulation of cell proliferation
regulation of circadian rhythm
positive regulation of MAP kinase activity
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of GTPase activity
negative regulation of epidermal cell differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
negative regulation of retinoic acid receptor signaling pathway
rhythmic process
negative regulation of striated muscle cell differentiation
cellular response to hydrogen peroxide
G1 to G0 transition
histone H3-K27 methylation
protein localization to chromatin
positive regulation of protein serine/threonine kinase activity
positive regulation of dendrite development
negative regulation of G1/S transition of mitotic cell cycle
core promoter binding
DNA binding
chromatin binding
RNA binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
chromatin DNA binding
histone methyltransferase activity
ribonucleoprotein complex binding
sequence-specific DNA binding
histone methyltransferase activity (H3-K27 specific)
promoter-specific chromatin binding

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