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Gene Symbol:
EZH2
Gene Name:
enhancer of zeste 2 polycomb repressive complex 2 subunit
Gene Aliases:
ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2
Chromosome Location:
Chr.7: 148807372 - 148884662 on Build GRCh38
UniGene ID:
Hs.444082
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 213529

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: EZH2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001203247.1 NP_001190176.1 7 877
NM_001203248.1 NP_001190177.1 7 850
NM_001203249.1 NP_001190178.1 7 977
NM_004456.4 NP_004447.2 7 877
NM_152998.2 NP_694543.1 6 760
XM_005249962.4 XP_005250019.1 7 3318
XM_005249963.4 XP_005250020.1 7 3291
XM_005249964.4 XP_005250021.1 7 3292
XM_011515883.2 XP_011514185.1 8 852
XM_011515884.2 XP_011514186.1 7 984
XM_011515885.2 XP_011514187.1 7 3293
XM_011515886.2 XP_011514188.1 8 1001
XM_011515887.2 XP_011514189.1 7 850
XM_011515888.2 XP_011514190.1 7 972
XM_011515889.2 XP_011514191.1 7 774
XM_011515890.2 XP_011514192.1 6 3203
XM_011515891.2 XP_011514193.1 5 937
XM_011515892.2 XP_011514194.1 7 3321
XM_011515893.2 XP_011514195.1 6 3201
XM_011515894.2 XP_011514196.1 6 702
XM_011515895.2 XP_011514197.1 6 3176
XM_011515896.2 XP_011514198.1 6 3202
XM_011515897.2 XP_011514199.1 8 1028
XM_011515898.2 XP_011514200.1 8 955
XM_011515899.2 XP_011514201.1 7 3323
XM_011515901.2 XP_011514203.1 7 3323
XM_017011817.1 XP_016867306.1 7 3319
XM_017011818.1 XP_016867307.1 8 1001
XM_017011819.1 XP_016867308.1 7 3319
XM_017011820.1 XP_016867309.1 6 733
XM_017011821.1 XP_016867310.1 8 1028
GenBank mRNA AB208895.1 - 7 811
AK092676.1 - 6 659
AK293239.1 - 7 788
AK302216.1 - 7 977
AK303585.1 - 7 815
AK303637.1 - 8 1029
AK314291.1 - 6 702
AY519465.1 - 6 684
BC010858.2 - 7 806 3901250
JF327843.1 - 5 567
U61145.1 - 7 773

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001134979, XM_006236404, XM_006236408, XM_006236403, XM_006236405, and others.
This siRNA also targets the following transcripts in Mouse: NM_007971, NM_001146689, BC016391, BC003772, U52951, and others.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
chromatin organization
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of epithelial to mesenchymal transition
regulation of gliogenesis
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
cerebellar cortex development
hippocampus development
response to estradiol
negative regulation of transcription elongation from RNA polymerase II promoter
regulation of cell proliferation
regulation of circadian rhythm
positive regulation of MAP kinase activity
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of GTPase activity
negative regulation of epidermal cell differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
negative regulation of retinoic acid receptor signaling pathway
rhythmic process
negative regulation of striated muscle cell differentiation
cellular response to hydrogen peroxide
G1 to G0 transition
histone H3-K27 methylation
protein localization to chromatin
positive regulation of protein serine/threonine kinase activity
positive regulation of dendrite development
negative regulation of G1/S transition of mitotic cell cycle
core promoter binding
DNA binding
chromatin binding
RNA binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
chromatin DNA binding
histone methyltransferase activity
ribonucleoprotein complex binding
sequence-specific DNA binding
histone methyltransferase activity (H3-K27 specific)
promoter-specific chromatin binding

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