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Gene Symbol:
Top2a
Gene Name:
topoisomerase (DNA) II alpha
Gene Aliases:
Top-2
Chromosome Location:
Chr.11: 98992947 - 99024206 on Build GRCm38
UniGene ID:
Mm.4237
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 187388

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Top2a
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_011623.2 NP_035753.2 6, 7 706
GenBank mRNA BC008170.1 - 6, 7 694
BC057873.1 - 6, 7 676
D12513.1 - 6, 7 632

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More Information


Gene Ontology Categories:

Function(s) Process(es)

resolution of meiotic recombination intermediates
sister chromatid segregation
hematopoietic progenitor cell differentiation
DNA metabolic process
DNA topological change
DNA ligation
DNA unwinding involved in DNA replication
cellular response to DNA damage stimulus
chromosome segregation
chromosome condensation
apoptotic chromosome condensation
embryonic cleavage
regulation of circadian rhythm
positive regulation of apoptotic process
mitotic DNA integrity checkpoint
positive regulation of viral genome replication
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
nucleotide binding
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
isomerase activity
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
sequence-specific DNA binding
structure-specific DNA binding
poly(A) RNA binding
metal ion binding
protein heterodimerization activity

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