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Gene Symbol:
App
Gene Name:
amyloid beta (A4) precursor protein
Gene Aliases:
Abeta, Abpp, Adap, Ag, Cvap, E030013M08Rik, betaApp
Chromosome Location:
Chr.16: 84954436 - 85173952 on Build GRCm38
UniGene ID:
Mm.277585
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 159691

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: App
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001198823.1 NP_001185752.1 3 483
NM_001198824.1 NP_001185753.1 3 483
NM_001198825.1 NP_001185754.1 3 483
NM_001198826.1 NP_001185755.1 3 483
NM_007471.3 NP_031497.2 3 483
GenBank mRNA AK128971.1 - 3 492
AK133639.1 - 3 480
AK147543.1 - 3 519
AK148439.1 - 3 355
AK159245.1 - 3 492
AK159352.1 - 3 490
AK159718.1 - 3 469
AK161976.1 - 3 459
AY267348.1 - 3 334
BC070409.1 - 3 479 5708093
M18373.1 - 3 472
U84012.1 - 3 472
X59379.1 - 3 402

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019288, XM_006248010, XM_006248009, XM_006248011, XM_006248008, and others.

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Function(s) Process(es)

suckling behavior
mRNA polyadenylation
regulation of translation
protein phosphorylation
cellular copper ion homeostasis
endocytosis
apoptotic process
response to oxidative stress
cell adhesion
regulation of epidermal growth factor-activated receptor activity
Notch signaling pathway
nervous system development
axonogenesis
mating behavior
locomotory behavior
axo-dendritic transport
cholesterol metabolic process
adult locomotory behavior
visual learning
negative regulation of peptidase activity
regulation of gene expression
negative regulation of endopeptidase activity
positive regulation of peptidase activity
positive regulation of G2/M transition of mitotic cell cycle
axon midline choice point recognition
neuron remodeling
dendrite development
extracellular matrix organization
forebrain development
neuron projection development
ionotropic glutamate receptor signaling pathway
regulation of multicellular organism growth
regulation of protein binding
negative regulation of neuron differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
collateral sprouting in absence of injury
regulation of synapse structure or activity
neuromuscular process controlling balance
synaptic growth at neuromuscular junction
protein homooligomerization
neuron apoptotic process
smooth endoplasmic reticulum calcium ion homeostasis
DNA binding
serine-type endopeptidase inhibitor activity
receptor binding
protein binding
heparin binding
peptidase activator activity
enzyme binding
peptidase inhibitor activity
acetylcholine receptor binding
identical protein binding
metal ion binding
transition metal ion binding
PTB domain binding
growth factor receptor binding

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