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Gene Symbol:
Lep
Gene Name:
leptin
Gene Aliases:
ob, obese
Chromosome Location:
Chr.6: 29060195 - 29073877 on Build GRCm38
UniGene ID:
Mm.277072
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID 155134

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Lep
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_008493.3 NP_032519.1 3 1000
GenBank mRNA AK030984.1 - 3 1000
AK142589.1 - 3 1003
BC125245.1 - 2 971 40054245
HQ166716.1 - 3 1000
U18812.1 - 3 997

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More Information


Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
ovulation from ovarian follicle
placenta development
regulation of protein phosphorylation
response to dietary excess
cardiac muscle hypertrophy
glucose metabolic process
regulation of gluconeogenesis
energy reserve metabolic process
glycerol biosynthetic process
lipid metabolic process
fatty acid beta-oxidation
signal transduction
tyrosine phosphorylation of STAT protein
cholesterol metabolic process
bile acid metabolic process
regulation of blood pressure
positive regulation of cell proliferation
adult feeding behavior
fatty acid catabolic process
negative regulation of metabolic process
regulation of metabolic process
central nervous system neuron development
insulin secretion
regulation of intestinal cholesterol absorption
negative regulation of appetite
response to insulin
leptin-mediated signaling pathway
positive regulation of peroxisome proliferator activated receptor signaling pathway
intracellular signal transduction
bone mineralization involved in bone maturation
positive regulation of protein import into nucleus
hormone metabolic process
positive regulation of tyrosine phosphorylation of Stat3 protein
glucose homeostasis
eating behavior
negative regulation of apoptotic process
positive regulation of ion transport
positive regulation of MAPK cascade
regulation of fat cell differentiation
positive regulation of myeloid cell differentiation
negative regulation of vasoconstriction
positive regulation of JAK-STAT cascade
positive regulation of insulin receptor signaling pathway
positive regulation of developmental growth
regulation of insulin secretion
regulation of steroid biosynthetic process
leukocyte tethering or rolling
regulation of lipoprotein lipid oxidation
adipose tissue development
negative regulation of cartilage development
negative regulation of glucagon secretion
regulation of protein localization to nucleus
positive regulation of STAT protein import into nucleus
positive regulation of reactive oxygen species metabolic process
negative regulation of glutamine transport
positive regulation of hepatic stellate cell activation
hormone activity
protein binding
growth factor activity
peptide hormone receptor binding

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