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Gene Symbol:
EZH2
Gene Name:
enhancer of zeste 2 polycomb repressive complex 2 subunit
Gene Aliases:
ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2
Chromosome Location:
Chr.7: 148807372 - 148884662 on Build GRCh38
UniGene ID:
Hs.444082
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 14733

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: EZH2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001203247.1 NP_001190176.1 3 392
NM_001203248.1 NP_001190177.1 3 392
NM_001203249.1 NP_001190178.1 3 519
NM_004456.4 NP_004447.2 3 392
NM_152998.2 NP_694543.1 3 392
XM_005249962.4 XP_005250019.1 3 2833
XM_005249963.4 XP_005250020.1 3 2833
XM_005249964.4 XP_005250021.1 3 2834
XM_011515883.2 XP_011514185.1 4 367
XM_011515884.2 XP_011514186.1 3 499
XM_011515885.2 XP_011514187.1 3 2835
XM_011515886.2 XP_011514188.1 3 364
XM_011515887.2 XP_011514189.1 3 392
XM_011515888.2 XP_011514190.1 3 514
XM_011515889.2 XP_011514191.1 2 179
XM_011515890.2 XP_011514192.1 3 2835
XM_011515892.2 XP_011514194.1 3 2836
XM_011515893.2 XP_011514195.1 3 2833
XM_011515894.2 XP_011514196.1 3 334
XM_011515895.2 XP_011514197.1 3 2835
XM_011515896.2 XP_011514198.1 3 2834
XM_011515897.2 XP_011514199.1 3 364
XM_011515898.2 XP_011514200.1 3 333
XM_011515899.2 XP_011514201.1 3 2838
XM_011515901.2 XP_011514203.1 3 2838
XM_017011817.1 XP_016867306.1 3 2834
XM_017011818.1 XP_016867307.1 3 364
XM_017011819.1 XP_016867308.1 3 2834
XM_017011820.1 XP_016867309.1 3 392
XM_017011821.1 XP_016867310.1 3 364
GenBank mRNA AB208895.1 - 3 326
AK092676.1 - 3 291
AK293239.1 - 3 330
AK302216.1 - 3 519
AK303585.1 - 3 330
AK303637.1 - 3 365
AK314291.1 - 3 334
AY519465.1 - 2 199
BC010858.2 - 3 321 3901250
BG829016.1 - 3 366
JF327843.1 - 2 199
U61145.1 - 3 288
X95653.1 - 3 256

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001134979, XM_006236404, XM_006236408, XM_006236403, XM_006236405, and others.

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
chromatin organization
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of epithelial to mesenchymal transition
regulation of gliogenesis
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
cerebellar cortex development
hippocampus development
response to estradiol
negative regulation of transcription elongation from RNA polymerase II promoter
regulation of cell proliferation
regulation of circadian rhythm
positive regulation of MAP kinase activity
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of GTPase activity
negative regulation of epidermal cell differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
negative regulation of retinoic acid receptor signaling pathway
rhythmic process
negative regulation of striated muscle cell differentiation
cellular response to hydrogen peroxide
G1 to G0 transition
histone H3-K27 methylation
protein localization to chromatin
positive regulation of protein serine/threonine kinase activity
positive regulation of dendrite development
negative regulation of G1/S transition of mitotic cell cycle
core promoter binding
DNA binding
chromatin binding
RNA binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
chromatin DNA binding
histone methyltransferase activity
ribonucleoprotein complex binding
sequence-specific DNA binding
histone methyltransferase activity (H3-K27 specific)
promoter-specific chromatin binding

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