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Gene Symbol:
GCLC
Gene Name:
glutamate-cysteine ligase catalytic subunit
Gene Aliases:
GCL, GCS, GLCL, GLCLC
Chromosome Location:
Chr.6: 53497341 - 53545129 on Build GRCh38
UniGene ID:
Hs.654465
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 144714

Purification
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Availability Inventoried
Catalog # AM16708
Price 261.00
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Online offer: 193.14
193.1
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: GCLC
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001197115.1 NP_001184044.1 15 3324
NM_001498.3 NP_001489.1 16 3438
XM_017010749.1 XP_016866238.1 16 3063
GenBank mRNA AB262176.1 - 16 3341
BC039894.1 - 16 3035 6052162

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010295, AK160876.

Gene Ontology Categories:

Function(s) Process(es)

sulfur amino acid metabolic process
cysteine metabolic process
glutamate metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
response to heat
response to xenobiotic stimulus
response to hormone
L-ascorbic acid metabolic process
negative regulation of protein ubiquitination
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell redox homeostasis
negative regulation of transcription, DNA-templated
response to arsenic-containing substance
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway
magnesium ion binding
glutamate-cysteine ligase activity
ATP binding
glutamate binding
ADP binding
protein heterodimerization activity
coenzyme binding

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