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See other SNCA SIRNA Assays ›
Gene Symbol:
SNCA
Gene Name:
synuclein alpha
Gene Aliases:
NACP, PARK1, PARK4, PD1
Chromosome Location:
Chr.4: 89724099 - 89838324 on Build GRCh38
UniGene ID:
Hs.21374
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 142087

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: SNCA
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000345.3 NP_000336.1 6 966
NM_001146054.1 NP_001139526.1 6 962
NM_001146055.1 NP_001139527.1 6 773
NM_007308.2 NP_009292.1 5 878
XM_011532208.2 XP_011530510.1 6 843
XM_017008562.1 XP_016864051.1 6 837
XM_017008563.1 XP_016864052.1 6 863
GenBank mRNA BC013293.2 - 6 1126 3604532
BC108275.1 - 6 920 6147966
D31839.1 - 4 632
JN709859.1 - 5 920
JN709860.1 - 4 836
JN709861.1 - 5 882
JN709862.1 - 5 924
JN709863.1 - 4 840
JN709864.1 - 5 689
JN709865.1 - 5 731
JN709866.1 - 4 647
JN709867.1 - 5 731
JN709868.1 - 5 773
JN709869.1 - 4 689
L08850.1 - 6 755

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_019169, AF007758, AY550005, BC087682, FQ227096, and others.
This siRNA also targets the following transcripts in Mouse: NM_009221, NM_001042451, BC046764, AF033261, AK156316, and others.

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
microglial cell activation
positive regulation of receptor recycling
negative regulation of protein phosphorylation
positive regulation of neurotransmitter secretion
fatty acid metabolic process
neutral lipid metabolic process
phospholipid metabolic process
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
mitochondrial membrane organization
aging
adult locomotory behavior
response to iron(II) ion
regulation of phospholipase activity
negative regulation of platelet-derived growth factor receptor signaling pathway
regulation of glutamate secretion
regulation of dopamine secretion
negative regulation of microtubule polymerization
receptor internalization
protein destabilization
response to magnesium ion
negative regulation of transporter activity
response to lipopolysaccharide
negative regulation of monooxygenase activity
positive regulation of peptidyl-serine phosphorylation
response to interferon-gamma
cellular response to oxidative stress
negative regulation of histone acetylation
regulation of locomotion
dopamine biosynthetic process
response to drug
mitochondrial ATP synthesis coupled electron transport
regulation of macrophage activation
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
extracellular fibril organization
negative regulation of neuron apoptotic process
cellular protein metabolic process
cellular response to fibroblast growth factor stimulus
positive regulation of endocytosis
negative regulation of exocytosis
negative regulation of dopamine metabolic process
behavioral response to cocaine
regulation of long-term neuronal synaptic plasticity
synaptic vesicle endocytosis
synapse organization
regulation of acyl-CoA biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
dopamine uptake involved in synaptic transmission
negative regulation of dopamine uptake involved in synaptic transmission
negative regulation of serotonin uptake
negative regulation of norepinephrine uptake
calcium ion homeostasis
oxidation-reduction process
excitatory postsynaptic potential
long-term synaptic potentiation
positive regulation of inositol phosphate biosynthetic process
negative regulation of thrombin receptor signaling pathway
response to interleukin-1
cellular response to copper ion
cellular response to epinephrine stimulus
positive regulation of protein serine/threonine kinase activity
negative regulation of neuron death
negative regulation of mitochondrial electron transport, NADH to ubiquinone
positive regulation of glutathione peroxidase activity
positive regulation of hydrogen peroxide catabolic process
regulation of synaptic vesicle recycling
regulation of reactive oxygen species biosynthetic process
negative regulation of chaperone-mediated autophagy
magnesium ion binding
fatty acid binding
copper ion binding
calcium ion binding
protein binding
phospholipid binding
microtubule binding
ferrous iron binding
zinc ion binding
oxidoreductase activity
kinesin binding
protein domain specific binding
histone binding
identical protein binding
alpha-tubulin binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
phospholipase binding
transcription regulatory region DNA binding
dynein binding
protein N-terminus binding
tau protein binding
beta-tubulin binding
phosphoprotein binding
phospholipase D inhibitor activity

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