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Gene Symbol:
MCL1
Gene Name:
BCL2 family apoptosis regulator
Gene Aliases:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Chromosome Location:
Chr.1: 150574551 - 150579738 on Build GRCh38
UniGene ID:
Hs.632486
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 120644
Validated

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Catalog # AM51331
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: MCL1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001197320.1 NP_001184249.1 4 1346
NM_021960.4 NP_068779.1 3 1805
NM_182763.2 NP_877495.1 2 1557
GenBank mRNA AF118124.1 - 3 1649
AK294462.1 - 4 1377
BC017197.2 - 3 1651 3138465
BC071897.1 - 3 1653 6586159
L08246.1 - 3 1660

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More Information


Matching Taqman Gene Expression Assay:


Hs00172036_m1

Gene Ontology Categories:

Function(s) Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway
protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding

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