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Gene Symbol:
MCL1
Gene Name:
BCL2 family apoptosis regulator
Gene Aliases:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Chromosome Location:
Chr.1: 150574551 - 150579738 on Build GRCh38
UniGene ID:
Hs.632486
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 120642
Validated

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Catalog # AM51331
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: MCL1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001197320.1 NP_001184249.1 4 784
NM_021960.4 NP_068779.1 3 1243
NM_182763.2 NP_877495.1 2 995
GenBank mRNA AF118124.1 - 3 1084
AF203373.1 - 2 787
AK294462.1 - 4 815
AK297217.1 - 4 779
AK300499.1 - 4 889
AK304775.1 - 4 925
AK312508.1 - 3 1115
AK316267.1 - 4 1071
BC017197.2 - 3 1089 3138465
BC071897.1 - 3 1091 6586159
BC107735.1 - 3 1106 4770487
BT006640.1 - 3 1035
FJ917536.1 - 4 576
L08246.1 - 3 1095

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More Information


Matching Taqman Gene Expression Assay:


Hs00172036_m1

Gene Ontology Categories:

Function(s) Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway
protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding

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