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Gene Symbol:
PCSK9
Gene Name:
proprotein convertase subtilisin/kexin type 9
Gene Aliases:
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9
Chromosome Location:
Chr.1: 55039476 - 55064853 on Build GRCh38
UniGene ID:
Hs.18844
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 113945

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PCSK9
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_174936.3 NP_777596.2 12 2500
NR_110451.1 10 1745
GenBank mRNA AK075365.1 - 12 2428
AK122717.1 - 13 2185
AK124635.1 - 8 2684

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More Information


Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Function(s) Process(es)

kidney development
liver development
negative regulation of receptor recycling
positive regulation of receptor internalization
triglyceride metabolic process
phospholipid metabolic process
apoptotic process
lysosomal transport
cholesterol metabolic process
cellular response to starvation
regulation of receptor activity
negative regulation of low-density lipoprotein particle clearance
protein autoprocessing
neurogenesis
neuron differentiation
low-density lipoprotein particle receptor catabolic process
positive regulation of low-density lipoprotein particle receptor catabolic process
cellular response to insulin stimulus
lipoprotein metabolic process
cholesterol homeostasis
regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
negative regulation of receptor activity
negative regulation of sodium ion transmembrane transporter activity
serine-type endopeptidase activity
protein binding
sodium channel inhibitor activity
low-density lipoprotein particle binding
receptor inhibitor activity
apolipoprotein binding
very-low-density lipoprotein particle binding
apolipoprotein receptor binding
protein self-association
poly(A) RNA binding
low-density lipoprotein particle receptor binding
very-low-density lipoprotein particle receptor binding

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