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Gene Symbol:
TLR4
Gene Name:
toll like receptor 4
Gene Aliases:
ARMD10, CD284, TLR-4, TOLL
Chromosome Location:
Chr.9: 117704175 - 117717491 on Build GRCh38
UniGene ID:
Hs.174312
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 112338

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: TLR4
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_003266.3 NP_003257.1 4 1969
NM_138554.4 NP_612564.1 3 1849
NM_138557.2 NP_612567.1 2 1682
GenBank mRNA AB445638.1 - 3 1551
AK226155.1 - 4 1724
AK290053.1 - 4 1952
AK293068.1 - 3 1680
AK303730.1 - 2 1513
BC025294.1 - 2 1468
BC117422.1 - 3 1571 40125973
BC143841.1 - 4 1691
U88880.1 - 4 1715
U93091.1 - 3 1654

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More Information


Gene Ontology Categories:

Function(s) Process(es)

activation of MAPK activity
toll-like receptor signaling pathway
B cell proliferation involved in immune response
nitric oxide production involved in inflammatory response
regulation of dendritic cell cytokine production
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
inflammatory response
immune response
I-kappaB kinase/NF-kappaB signaling
I-kappaB phosphorylation
positive regulation of platelet activation
positive regulation of gene expression
astrocyte development
detection of fungus
positive regulation of B cell proliferation
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
detection of lipopolysaccharide
interferon-gamma production
negative regulation of interferon-gamma production
negative regulation of interleukin-17 production
negative regulation of interleukin-23 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of chemokine production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
negative regulation of MyD88-independent toll-like receptor signaling pathway
toll-like receptor 4 signaling pathway
TRIF-dependent toll-like receptor signaling pathway
T-helper 1 type immune response
macrophage activation
positive regulation of NF-kappaB import into nucleus
positive regulation of tumor necrosis factor biosynthetic process
defense response to bacterium
positive regulation of interleukin-12 biosynthetic process
innate immune response
positive regulation of MHC class II biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of interleukin-8 biosynthetic process
positive regulation of nitric oxide biosynthetic process
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
interleukin-1 beta secretion
regulation of cytokine secretion
positive regulation of inflammatory response
defense response to Gram-negative bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
intestinal epithelial structure maintenance
positive regulation of macrophage cytokine production
necroptotic process
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
cellular response to lipopolysaccharide
cellular response to lipoteichoic acid
cellular response to mechanical stimulus
apoptotic signaling pathway
positive regulation of NLRP3 inflammasome complex assembly
lipopolysaccharide binding
lipopolysaccharide receptor activity
receptor activity
transmembrane signaling receptor activity
protein binding

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