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Gene Symbol:
DOT1L
Gene Name:
DOT1 like histone lysine methyltransferase
Gene Aliases:
DOT1, KMT4
Chromosome Location:
Chr.19: 2163963 - 2232578 on Build GRCh38
UniGene ID:
Hs.713641
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 112262
Validated

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Catalog # AM51331
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: DOT1L
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_032482.2 NP_115871.1 3 200
XM_005259659.3 XP_005259716.1 3 386
XM_005259660.3 XP_005259717.1 3 386
XM_011528359.2 XP_011526661.1 3 386
XM_011528360.1 XP_011526662.1 3 151
XM_017027366.1 XP_016882855.1 3 386
GenBank mRNA AF509504.1 - 3 200

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More Information


Matching Taqman Gene Expression Assay:


Hs00287200_m1

Gene Ontology Categories:

Function(s) Process(es)

chromatin silencing
positive regulation of cell proliferation
telomere organization
histone H3-K79 methylation
positive regulation of transcription from RNA polymerase II promoter
regulation of JAK-STAT cascade
regulation of cell cycle
regulation of transcription regulatory region DNA binding
DNA binding
protein binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K79 specific)
histone methyltransferase activity

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