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Gene Symbol:
HMGCR
Gene Name:
3-hydroxy-3-methylglutaryl-CoA reductase
Gene Aliases:
LDLCQ3
Chromosome Location:
Chr.5: 75336334 - 75362101 on Build GRCh38
UniGene ID:
Hs.628096
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 110740
Validated

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Catalog # AM51331
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: HMGCR
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000859.2 NP_000850.1 2, 3 329
NM_001130996.1 NP_001124468.1 2, 3 329
XM_011543357.1 XP_011541659.1 2, 3 480
XM_011543358.1 XP_011541660.1 2, 3 367
XM_011543359.1 XP_011541661.1 2, 3 480
GenBank mRNA AK292892.1 - 2, 3 260
AK296499.1 - 2, 3 485
AK312437.1 - 1, 2 173
BC033692.1 - 2, 3 265 5212903
M11058.1 - 2, 3 223

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More Information


Matching Taqman Gene Expression Assay:


Hs00168352_m1

Gene Ontology Categories:

Function(s) Process(es)

cholesterol biosynthetic process
ubiquinone metabolic process
aging
response to nutrient
isoprenoid biosynthetic process
visual learning
negative regulation of striated muscle cell apoptotic process
positive regulation of cardiac muscle cell apoptotic process
coenzyme A metabolic process
positive regulation of stress-activated MAPK cascade
negative regulation of MAP kinase activity
myoblast differentiation
response to ethanol
negative regulation of vasodilation
positive regulation of skeletal muscle tissue development
positive regulation of smooth muscle cell proliferation
protein tetramerization
oxidation-reduction process
negative regulation of wound healing
negative regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of ERK1 and ERK2 cascade
hydroxymethylglutaryl-CoA reductase (NADPH) activity
protein binding
hydroxymethylglutaryl-CoA reductase activity
protein homodimerization activity
coenzyme binding
protein phosphatase 2A binding
NADPH binding

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