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Gene Symbol:
GCLC
Gene Name:
glutamate-cysteine ligase catalytic subunit
Gene Aliases:
GCL, GCS, GLCL, GLCLC
Chromosome Location:
Chr.6: 53497341 - 53545129 on Build GRCh38
UniGene ID:
Hs.654465
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 106476
Validated

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Catalog # AM51331
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: GCLC
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001197115.1 NP_001184044.1 3 879
NM_001498.3 NP_001489.1 3 879
XM_017010749.1 XP_016866238.1 3 469
GenBank mRNA AB262176.1 - 3 782
AB516284.1 - 3 395
AK304288.1 - 3 407
AK313480.1 - 3 789
BC022487.1 - 3 786
BC039894.1 - 3 477 6052162
M90656.1 - 3 487

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More Information


Matching Taqman Gene Expression Assay:


Hs00155249_m1

Gene Ontology Categories:

Function(s) Process(es)

sulfur amino acid metabolic process
cysteine metabolic process
glutamate metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
response to heat
response to xenobiotic stimulus
response to hormone
L-ascorbic acid metabolic process
negative regulation of protein ubiquitination
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
cell redox homeostasis
negative regulation of transcription, DNA-templated
response to arsenic-containing substance
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway
magnesium ion binding
glutamate-cysteine ligase activity
ATP binding
glutamate binding
ADP binding
protein heterodimerization activity
coenzyme binding

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