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Gene Symbol:
PTPN6
Gene Name:
protein tyrosine phosphatase, non-receptor type 6
Gene Aliases:
HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, SHP1
Chromosome Location:
Chr.12: 6946576 - 6961316 on Build GRCh38
UniGene ID:
Hs.63489
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 105912

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PTPN6
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_002831.5 NP_002822.2 6 949
NM_080548.4 NP_536858.1 6 862
NM_080549.3 NP_536859.1 6 949
XM_006718994.1 XP_006719057.1 6 1006
XM_011520988.1 XP_011519290.1 6 863
GenBank mRNA AF178946.1 - 6 731
AK223629.1 - 6 844
AK290421.1 - 6 832
AK298470.1 - 5 1115
AK300167.1 - 5 706
AK308230.1 - 6 897
AK313379.1 - 6 862
BC002523.2 - 6 848 3140265
BC007667.2 - 6 848 3138804
BT007390.1 - 5 713
M74903.1 - 6 790
M77273.1 - 6 851

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More Information


Gene Ontology Categories:

Function(s) Process(es)

hematopoietic progenitor cell differentiation
negative regulation of humoral immune response mediated by circulating immunoglobulin
protein dephosphorylation
apoptotic process
G-protein coupled receptor signaling pathway
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
cell differentiation
platelet activation
platelet formation
T cell costimulation
abortive mitotic cell cycle
positive regulation of cell adhesion mediated by integrin
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
megakaryocyte development
negative regulation of T cell proliferation
natural killer cell mediated cytotoxicity
negative regulation of MAP kinase activity
regulation of B cell differentiation
negative regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
leukocyte migration
regulation of release of sequestered calcium ion into cytosol
regulation of type I interferon-mediated signaling pathway
regulation of ERK1 and ERK2 cascade
platelet aggregation
regulation of G1/S transition of mitotic cell cycle
phosphotyrosine binding
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
SH3 domain binding
protein kinase binding
SH2 domain binding

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