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Gene Symbol:
PTPN2
Gene Name:
protein tyrosine phosphatase, non-receptor type 2
Gene Aliases:
PTN2, PTPT, TC-PTP, TCELLPTP, TCPTP
Chromosome Location:
Chr.18: 12785478 - 12884351 on Build GRCh38
UniGene ID:
Hs.654527
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 105836

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PTPN2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001207013.1 NP_001193942.1 2 342
NM_002828.3 NP_002819.2 2 342
NM_080422.2 NP_536347.1 2 342
NM_080423.2 NP_536348.1 2 342
XM_005258124.3 XP_005258181.1 2 340
XM_005258125.3 XP_005258182.1 2 340
XM_011525705.2 XP_011524007.1 2 311
XM_011525706.2 XP_011524008.1 2 265
XM_017025884.1 XP_016881373.1 2 358
XM_017025885.1 XP_016881374.1 2 295
GenBank mRNA AK225706.1 - 2 221
AK290649.1 - 2 224
AK292570.1 - 2 242
BC008244.1 - 2 185 3872164
BC016727.1 - 2 254 4081330
BG699440.1 - 2 347
M25393.1 - 2 208

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053990, XM_008772080, XM_006254854, XM_006254855, XM_008772081, and others.
This siRNA also targets the following transcripts in Mouse: NM_001127177, NM_008977, BC008269, AK076072, M80739, and others.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of cell proliferation
insulin receptor signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of lipid storage
B cell differentiation
T cell differentiation
erythrocyte differentiation
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of tyrosine phosphorylation of Stat6 protein
glucose homeostasis
negative regulation of macrophage differentiation
positive regulation of gluconeogenesis
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
negative regulation of T cell receptor signaling pathway
negative regulation of chemotaxis
regulation of interferon-gamma-mediated signaling pathway
negative regulation of interferon-gamma-mediated signaling pathway
negative regulation of type I interferon-mediated signaling pathway
negative regulation of protein tyrosine kinase activity
negative regulation of interleukin-6-mediated signaling pathway
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of interleukin-2-mediated signaling pathway
negative regulation of prolactin signaling pathway
negative regulation of interleukin-4-mediated signaling pathway
negative regulation of macrophage colony-stimulating factor signaling pathway
negative regulation of positive thymic T cell selection
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
negative regulation of platelet-derived growth factor receptor-beta signaling pathway
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
integrin binding
protein binding
protein kinase binding
syntaxin binding
receptor tyrosine kinase binding

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