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Gene Symbol:
PLK1
Gene Name:
polo like kinase 1
Gene Aliases:
PLK, STPK13
Chromosome Location:
Chr.16: 23678772 - 23690367 on Build GRCh38
UniGene ID:
Hs.592049
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID 103548
Validated

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Catalog # AM51331
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PLK1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_005030.5 NP_005021.2 3 862
GenBank mRNA AB209179.1 - 2 2721
AK303263.1 - 4 478
AK308276.1 - 4 719
AK313227.1 - 3 786
BC002369.2 - 3 754 2822226
BC003002.1 - 3 732 2823623
BC014846.1 - 3 707 3854860
L19559.1 - 3 764
U01038.1 - 3 764
X73458.1 - 3 778
X75932.1 - 3 764

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011121, AK148076, BC006880, AK134045, L19558, and others.

Matching Taqman Gene Expression Assay:


Hs00153444_m1

Gene Ontology Categories:

Function(s) Process(es)

mitotic sister chromatid segregation
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
mitotic cytokinesis
cytokinesis
microtubule bundle formation
protein phosphorylation
sister chromatid cohesion
mitotic nuclear division
mitotic nuclear envelope disassembly
mitotic spindle assembly checkpoint
regulation of mitotic cell cycle
cell proliferation
positive regulation of peptidyl-threonine phosphorylation
female meiosis chromosome segregation
protein ubiquitination
peptidyl-serine phosphorylation
regulation of mitotic metaphase/anaphase transition
anaphase-promoting complex-dependent catabolic process
G2 DNA damage checkpoint
protein destabilization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
regulation of protein binding
homologous chromosome segregation
establishment of protein localization
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of proteolysis
centrosome organization
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein transferase activity
regulation of cell cycle
synaptonemal complex disassembly
protein localization to chromatin
positive regulation of protein localization to nucleus
regulation of mitotic spindle assembly
regulation of cell cycle G2/M phase transition
positive regulation of ubiquitin protein ligase activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
microtubule binding
anaphase-promoting complex binding
kinase activity
protein kinase binding

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