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See other B2M GE Assays ›
Gene Symbol:
B2m
Gene Name:
beta-2 microglobulin
Gene Aliases:
Ly-m11, beta2-m, beta2m
Chromosome Location:
Chr.2: 122147687 - 122153082 on Build GRCm38
Species:
Mouse
Species Specific ID (Flybase ID):
-
Assay ID Mm00437762_m1
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Catalog # 4331182
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  • Genomic Map
  • Assay Details
  • More Information
  • Citations (31)

Genomic Map

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Assay Details

Gene Symbol: B2m
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_009735.3 NP_033865.2 1 - 2 111 77
GenBank mRNA AK019389.1 - 1 - 2 114 77
AK028378.1 - 1 - 2 113 77
AK153255.1 - 1 - 2 113 77
AK166067.1 - 1 - 2 114 77
BC085164.1 - 1 - 2 66 6846389 77
X01838.1 - 1 - 2 77

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More Information


Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200001838.mm.1

Set Membership:

Ambion siRNA available Amplicon length between 71 and 85 Mammalian Gene Collection Endogenous Controls Recommended Assay Mus musculus Mouse Endogenous Controls Inventoried Mouse_Endogenous_Controls Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene B2m

Panther Classification:

Molecular Function -

major histocompatibility complex protein

Gene Ontology Categories:

Function(s) Process(es)

positive regulation of T cell mediated cytotoxicity
response to molecule of bacterial origin
immune system process
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
cellular defense response
T cell differentiation in thymus
protein refolding
iron ion homeostasis
negative regulation of receptor binding
glycoprotein binding
protein binding
identical protein binding

MicroArray Probes:

Affymetrix

Array Name Probe IDs Targets Target Type
Affymetrix Mouse Clariom S Array PSR0200014262.mm.1 NM_009735.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR0200014262.mm.1 NM_009735.3 Refseq
Affymetrix Mouse Clariom S Array PSR0200014262.mm.1 TC0200001838.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR0200014267.mm.1 NM_009735.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR0200014267.mm.1 NM_009735.3 Refseq
Affymetrix Mouse Clariom S Array PSR0200014267.mm.1 TC0200001838.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR0200014264.mm.1 NM_009735.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR0200014264.mm.1 NM_009735.3 Refseq
Affymetrix Mouse Clariom S Array PSR0200014264.mm.1 TC0200001838.mm.1 MTA TC

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Citations (31)

Gene expression profiling in the lung and liver of PFOA-exposed mouse fetuses.
Authors
Rosen MB, Thibodeaux JR, Wood CR, Zehr RD, Schmid JE, Lau C
Journal
Toxicology - Page No 15 (Mon Sep 24 00:00:00 UTC 2007)
Volume (Year)
239 (2007)
Product Usage
-
Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates.
Authors
Bruss MD, Khambatta CF, Ruby MA, Aggarwal I, Hellerstein MK
Journal
Am J Physiol Endocrinol Metab - Page No E108 (Fri Jan 01 00:00:00 UTC 2010)
Volume (Year)
298 (2010)
Product Usage
-
Plasticity of proximal-distal cell fate in the mammalian limb bud.
Authors
Wyngaarden LA, Hopyan S
Journal
Dev Biol - Page No 225 (Tue Jan 01 00:00:00 UTC 2008)
Volume (Year)
313 (2008)
Product Usage
-
Interleukin-6 trans-signaling regulates glycogen consumption after D-galactosamine-induced liver damage.
Authors
Drucker C, Rabe B, Chalaris A, Schulz E, Scheller J, Rose-John S
Journal
J Interferon Cytokine Res - Page No 711 (Sun Nov 01 00:00:00 UTC 2009)
Volume (Year)
29 (2009)
Product Usage
-
Transcriptomic comparison of the retina in two mouse models of diabetes.
Authors
Freeman WM, Bixler GV, Brucklacher RM, Walsh E, Kimball SR, Jefferson LS, Bronson SK
Journal
J Ocul Biol Dis Infor - Page No 202 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
2 (2009)
Product Usage
-
Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblasts.
Authors
Matheny RW Jr, Adamo ML
Journal
Biochem Biophys Res Commun - Page No 252 (Fri Dec 11 00:00:00 UTC 2009)
Volume (Year)
390 (2009)
Product Usage
-
Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: comparison to changes induced by exposure to perfluorooctanoic acid.
Authors
Rosen MB, Schmid JE, Das KP, Wood CR, Zehr RD, Lau C
Journal
Reprod Toxicol - Page No 278 (Mon Jun 01 00:00:00 UTC 2009)
Volume (Year)
27 (2009)
Product Usage
-
Growth hormone-releasing peptide-2 stimulates secretion and synthesis of adrenocorticotropic hormone in mouse pituitary.
Authors
Kageyama K, Kushibiki M, Hanada K, Sakihara S, Yasujima M, Suda T
Journal
Regul Pept - Page No 116 (Fri Nov 27 00:00:00 UTC 2009)
Volume (Year)
158 (2009)
Product Usage
-
Differential expression of interferon (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts.
Authors
Scherbik SV, Stockman BM, Brinton MA
Journal
J Virol - Page No 12005 (Thu Nov 01 00:00:00 UTC 2007)
Volume (Year)
81 (2007)
Product Usage
-
Gender-dependent expression of murine Irf5 gene: implications for sex bias in autoimmunity.
Authors
Shen H, Panchanathan R, Rajavelu P, Duan X, Gould KA, Choubey D
Journal
J Mol Cell Biol - Page No 284 (Fri Oct 01 00:00:00 UTC 2010)
Volume (Year)
2 (2010)
Product Usage
-
Mouse embryo fibroblasts lacking the tumor suppressor menin show altered expression of extracellular matrix protein genes.
Authors
Ji Y, Prasad NB, Novotny EA, Kaur S, Elkahloun A, Chen Y, Zhang RZ, Chu ML, Agarwal SK, Marx SJ, Collins FS, Chandrasekharappa SC
Journal
Mol Cancer Res - Page No 1041 (Mon Oct 01 00:00:00 UTC 2007)
Volume (Year)
5 (2007)
Product Usage
-
Genetic control of resistance to hepatocarcinogenesis by the mouse Hpcr3 locus.
Authors
Manenti G, Galvan A, Falvella FS, Pascale RM, Spada E, Milani S, Gonzalez Neira A, Feo F, Dragani TA
Journal
Hepatology - Page No 617 (Fri Aug 01 00:00:00 UTC 2008)
Volume (Year)
48 (2008)
Product Usage
-
Stimulation of osteoblasts with Emdogain increases the expression of specific mineralization markers.
Authors
Weishaupt P, Bernimoulin JP, Trackman P, Hagewald S
Journal
Oral Surg Oral Med Oral Pathol Oral Radiol Endod - Page No 304 (Fri Aug 01 00:00:00 UTC 2008)
Volume (Year)
106 (2008)
Product Usage
-
Early organ-specific endothelial activation during hemorrhagic shock and resuscitation.
Authors
van Meurs M, Wulfert FM, Knol AJ, De Haes A, Houwertjes M, Aarts LP, Molema G
Journal
Shock - Page No 291 (Fri Feb 01 00:00:00 UTC 2008)
Volume (Year)
29 (2008)
Product Usage
-
Molecular structure of tail tendon fibers in TIEG1 knockout mice using synchrotron diffraction technology.
Authors
Gumez L, Bensamoun SF, Doucet J, Haddad O, Hawse JR, Subramaniam M, Spelsberg TC, Pichon C
Journal
J Appl Physiol - Page No 1706 (Tue Jun 01 00:00:00 UTC 2010)
Volume (Year)
108 (2010)
Product Usage
-
Selection of reference genes for quantitative real-time RT-PCR studies in mouse brain.
Authors
Boda E, Pini A, Hoxha E, Parolisi R, Tempia F
Journal
J Mol Neurosci - Page No 238 (Sun Mar 01 00:00:00 UTC 2009)
Volume (Year)
37 (2009)
Product Usage
-
PDGF-Ralpha gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts.
Authors
Kimani PW, Holmes AJ, Grossmann RE, McGowan SE
Journal
Respir Res - Page No 119 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
10 (2009)
Product Usage
-
Gene expression fluctuations in murine hematopoietic stem cells with cell cycle progression.
Authors
Dooner GJ, Colvin GA, Dooner MS, Johnson KW, Quesenberry PJ
Journal
J Cell Physiol - Page No 786 (Sat Mar 01 00:00:00 UTC 2008)
Volume (Year)
214 (2008)
Product Usage
-
The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity.
Authors
Bonnet N, Standley KN, Bianchi EN, Stadelmann V, Foti M, Conway SJ, Ferrari SL
Journal
J Biol Chem - Page No 35939 (Fri Dec 18 00:00:00 UTC 2009)
Volume (Year)
284 (2009)
Product Usage
-
Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.
Authors
Pischon N, Maki JM, Weisshaupt P, Heng N, Palamakumbura AH, N'Guessan P, Ding A, Radlanski R, Renz H, Bronckers TA, Myllyharju J, Kielbassa AM, Kleber BM, Bernimoulin JP, Trackman PC
Journal
Calcif Tissue Int - Page No 119 (Sat Aug 01 00:00:00 UTC 2009)
Volume (Year)
85 (2009)
Product Usage
-
Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.
Authors
Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H
Journal
Cancer Lett - Page No 177 (Sun Feb 28 00:00:00 UTC 2010)
Volume (Year)
288 (2010)
Product Usage
-
Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.
Authors
Fairhurst AM, Xie C, Fu Y, Wang A, Boudreaux C, Zhou XJ, Cibotti R, Coyle A, Connolly JE, Wakeland EK, Mohan C
Journal
J Immunol - Page No 6831 (Sun Nov 15 00:00:00 UTC 2009)
Volume (Year)
183 (2009)
Product Usage
-
Cyanidin 3-glucoside ameliorates hyperglycemia and insulin sensitivity due to downregulation of retinol binding protein 4 expression in diabetic mice.
Authors
Sasaki R, Nishimura N, Hoshino H, Isa Y, Kadowaki M, Ichi T, Tanaka A, Nishiumi S, Fukuda I, Ashida H, Horio F, Tsuda T
Journal
Biochem Pharmacol - Page No 1619 (Mon Dec 03 00:00:00 UTC 2007)
Volume (Year)
74 (2007)
Product Usage
-
Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function.
Authors
Huth T, Schmidt-Neuenfeldt K, Rittger A, Saftig P, Reiss K, Alzheimer C
Journal
Neurobiol Dis - Page No 282 (Sun Feb 01 00:00:00 UTC 2009)
Volume (Year)
33 (2009)
Product Usage
-
Invariant natural killer T cell-natural killer cell interactions dictate transplantation outcome after alpha-galactosylceramide administration.
Authors
Kuns RD, Morris ES, Macdonald KP, Markey KA, Morris HM, Raffelt NC, Banovic T, Don AL, Rowe V, Burman AC, Clouston AD, Farah C, Besra GS, Illarionov PA, Smyth MJ, Porcelli SA, Hill GR
Journal
Blood - Page No 5999 (Thu Jun 04 00:00:00 UTC 2009)
Volume (Year)
113 (2009)
Product Usage
-
Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription.
Authors
Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ
Journal
Exp Hematol - Page No 233 (Mon Mar 01 00:00:00 UTC 2010)
Volume (Year)
38 (2010)
Product Usage
-
Activation of antioxidative enzymes induced by low-dose-rate whole-body gamma irradiation: adaptive response in terms of initial DNA damage.
Authors
Otsuka K, Koana T, Tauchi H, Sakai K
Journal
Radiat Res - Page No 474 (Fri Sep 01 00:00:00 UTC 2006)
Volume (Year)
166 (2006)
Product Usage
-
Involvement of nuclear factor-kB and Nurr-1 in cytokine-induced transcription of proopiomelanocortin gene in AtT20 corticotroph cells.
Authors
Takayasu S, Iwasaki Y, Nigawara T, Asai M, Yoshida M, Kageyama K, Suda T
Journal
Neuroimmunomodulation - Page No 88 (Fri Jan 01 00:00:00 UTC 2010)
Volume (Year)
17 (2010)
Product Usage
-
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice.
Authors
Granger A, Abdullah I, Huebner F, Stout A, Wang T, Huebner T, Epstein JA, Gruber PJ
Journal
Faseb J - Page No 3549 (Wed Oct 01 00:00:00 UTC 2008)
Volume (Year)
22 (2008)
Product Usage
-
PI3K p110 alpha and p110 beta have differential effects on Akt activation and protection against oxidative stress-induced apoptosis in myoblasts.
Authors
Matheny RW Jr, Adamo ML
Journal
Cell Death Differ - Page No 677 (Thu Apr 01 00:00:00 UTC 2010)
Volume (Year)
17 (2010)
Product Usage
-
Dehydroepiandrosterone modulates toll-like receptor expression on splenic macrophages of mice after severe polymicrobial sepsis.
Authors
Matsuda A, Furukawa K, Suzuki H, Matsutani T, Tajiri T, Chaudry IH
Journal
Shock - Page No 364 (Sat Oct 01 00:00:00 UTC 2005)
Volume (Year)
24 (2005)
Product Usage
-

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