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See other VEGFA GE Assays ›
Gene Symbol:
Vegfa
Gene Name:
vascular endothelial growth factor A
Gene Aliases:
Vegf, Vpf
Chromosome Location:
Chr.17: 46016993 - 46032377 on Build GRCm38
Species:
Mouse
Species Specific ID (Flybase ID):
-
Assay ID Mm00437304_m1
Size
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Catalog # 4331182
Price 244.00
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  • Genomic Map
  • Assay Details
  • More Information
  • Citations (27)

Genomic Map

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Assay Details

Gene Symbol: Vegfa
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_001025250.3 NP_001020421.2 1 - 2 1087 77
NM_001025257.3 NP_001020428.2 1 - 2 1087 77
NM_001287056.1 NP_001273985.1 1 - 2 1087 77
NM_001287057.1 NP_001273986.1 1 - 2 1087 77
NM_001287058.1 NP_001273987.1 1 - 2 1087 77
NM_009505.4 NP_033531.3 1 - 2 1087 77
GenBank mRNA AY263146.1 - 1 - 2 66 77
AY707864.1 - 2 - 3 284 77
AY750956.1 - 2 - 3 245 77
AY750957.1 - 2 - 3 208 77
BC061468.1 - 1 - 2 460 6816435 77
CA321456.1 - 1 - 2 460 77
EF028705.1 - 2 - 3 280 77
M95200.1 - 1 - 2 152 77
S37052.1 - 1 - 2 78 77
S38083.1 - 1 - 2 78 77
S38100.1 - 1 - 2 78 77
U50279.1 - 1 - 2 66 77

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More Information


Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700002162.mm.1

Set Membership:

Ambion siRNA available Amplicon length between 71 and 85 Mammalian Gene Collection Mus musculus Mouse Immune Response 1700 Inventoried Mouse_Immune_Response Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Vegfa

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
ovarian follicle development
blood vessel development
patterning of blood vessels
response to hypoxia
in utero embryonic development
kidney development
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
vasculature development
lymphangiogenesis
blood vessel remodeling
sprouting angiogenesis
cell migration involved in sprouting angiogenesis
positive regulation of neuroblast proliferation
positive regulation of mesenchymal cell proliferation
positive regulation of receptor internalization
basophil chemotaxis
heart morphogenesis
outflow tract morphogenesis
coronary vein morphogenesis
regulation of transcription from RNA polymerase II promoter
multicellular organism development
nervous system development
mesoderm development
lactation
cell proliferation
positive regulation of cell proliferation
regulation of cell shape
positive regulation of signal transduction
positive regulation of endothelial cell migration
positive regulation of gene expression
cell migration
negative regulation of cell-cell adhesion
cell differentiation
monocyte differentiation
macrophage differentiation
lung development
positive regulation of cell migration
regulation of cGMP metabolic process
epithelial cell differentiation
positive regulation of vascular endothelial growth factor receptor signaling pathway
post-embryonic camera-type eye development
positive regulation of protein complex assembly
positive regulation of protein autophosphorylation
activation of protein kinase activity
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
tube formation
endothelial cell chemotaxis
cellular response to vascular endothelial growth factor stimulus
lymph vessel morphogenesis
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
vascular endothelial growth factor signaling pathway
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
VEGF-activated neuropilin signaling pathway
growth
T-helper 1 type immune response
eye photoreceptor cell development
negative regulation of apoptotic process
negative regulation of programmed cell death
positive regulation of vascular permeability
surfactant homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAP kinase activity
negative regulation of neuron apoptotic process
positive regulation of blood vessel endothelial cell migration
endothelial cell migration
regulation of endothelial cell differentiation
positive regulation of angiogenesis
negative regulation of bone resorption
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
vascular endothelial growth factor receptor signaling pathway
mRNA stabilization
lung alveolus development
cell maturation
blood vessel morphogenesis
camera-type eye morphogenesis
positive regulation of smooth muscle cell proliferation
neuron development
cardiac muscle fiber development
branching morphogenesis of an epithelial tube
positive regulation of axon extension involved in axon guidance
artery morphogenesis
positive regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
positive regulation of positive chemotaxis
induction of positive chemotaxis
positive regulation of cellular component movement
positive regulation of cell division
positive regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
primitive erythrocyte differentiation
cell chemotaxis
lung vasculature development
mammary gland alveolus development
positive regulation of mast cell chemotaxis
cardiac vascular smooth muscle cell development
angiogenesis involved in coronary vascular morphogenesis
coronary artery morphogenesis
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
positive regulation of ERK1 and ERK2 cascade
cellular response to hypoxia
dopaminergic neuron differentiation
commissural neuron axon guidance
positive regulation of protein kinase C signaling
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of branching involved in ureteric bud morphogenesis
regulation of retinal ganglion cell axon guidance
positive regulation of peptidyl-tyrosine autophosphorylation
positive regulation of p38MAPK cascade
negative regulation of neuron death
positive regulation of lymphangiogenesis
regulation of hematopoietic progenitor cell differentiation
positive regulation of histone deacetylase activity
positive regulation of retinal ganglion cell axon guidance
positive regulation of protein localization to early endosome
positive regulation of protein kinase D signaling
positive regulation of receptor activity
negative regulation of extrinsic apoptotic signaling pathway
fibronectin binding
receptor binding
cytokine activity
platelet-derived growth factor receptor binding
vascular endothelial growth factor receptor binding
protein binding
growth factor activity
heparin binding
neuropilin binding
chemoattractant activity
identical protein binding
protein homodimerization activity
vascular endothelial growth factor receptor 1 binding
vascular endothelial growth factor receptor 2 binding
protein heterodimerization activity
receptor agonist activity
extracellular matrix binding

MicroArray Probes:

Affymetrix ABI

Array Name Probe IDs Targets Target Type
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001025250.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001025250.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001025257.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001025257.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001287056.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001287057.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_001287058.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_009505.4.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 NM_009505.4 Refseq
Affymetrix Mouse Clariom S Array PSR1700020309.mm.1 TC1700002162.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001025250.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001025250.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001025257.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001025257.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001287056.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001287057.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_001287058.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_009505.4.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 NM_009505.4 Refseq
Affymetrix Mouse Clariom S Array PSR1700020305.mm.1 TC1700002162.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001025250.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001025250.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001025257.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001025257.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001287056.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001287057.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_001287058.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_009505.4.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 NM_009505.4 Refseq
Affymetrix Mouse Clariom S Array PSR1700020307.mm.1 TC1700002162.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001025250.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001025250.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001025257.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001025257.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001287056.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001287057.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_001287058.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_009505.4.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 NM_009505.4 Refseq
Affymetrix Mouse Clariom S Array PSR1700020306.mm.1 TC1700002162.mm.1 MTA TC
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001025250.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001025250.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001025257.3.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001025257.3 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001287056.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001287057.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_001287058.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_009505.4.1 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 NM_009505.4 Refseq
Affymetrix Mouse Clariom S Array PSR1700020308.mm.1 TC1700002162.mm.1 MTA TC
Array Name Probe IDs Targets Target Type
ABI Mouse Genome Survey Microarray 620740 - -

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Citations (27)

Parathyroid hormone-related protein promotes epithelial-mesenchymal transition.
Authors
Ardura JA, Rayego-Mateos S, Ramila D, Ruiz-Ortega M, Esbrit P
Journal
J Am Soc Nephrol - Page No 237 (Mon Feb 01 00:00:00 UTC 2010)
Volume (Year)
21 (2010)
Product Usage
-
Mechanisms of sex differences in TNFR2-mediated cardioprotection.
Authors
Wang M, Crisostomo PR, Markel TA, Wang Y, Meldrum DR
Journal
Circulation - Page No S38 (Tue Sep 30 00:00:00 UTC 2008)
Volume (Year)
118 (2008)
Product Usage
-
Oral iron chelator deferiprone protects against iron overload induced retinal degeneration.
Authors
Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Grieco S, Lee J, Lyubarsky A, Pratico D, Connelly J, Spino M, Harris ZL, Dunaief J
Journal
Invest Ophthalmol Vis Sci - Page No (Thu Nov 04 00:00:00 UTC 2010)
Volume (Year)
 (2010)
Product Usage
-
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas.
Authors
Park E, Zhu F, Liu B, Xia X, Shen J, Bustos T, Fischer SM, Hu Y
Journal
Cancer Res - Page No 9158 (Mon Oct 01 00:00:00 UTC 2007)
Volume (Year)
67 (2007)
Product Usage
-
Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2.
Authors
Le XF, Mao W, Lu C, Thornton A, Heymach JV, Sood AK, Bast RC Jr
Journal
Cell Cycle - Page No 3747 (Mon Dec 01 00:00:00 UTC 2008)
Volume (Year)
7 (2008)
Product Usage
-
Early organ-specific endothelial activation during hemorrhagic shock and resuscitation.
Authors
van Meurs M, Wulfert FM, Knol AJ, De Haes A, Houwertjes M, Aarts LP, Molema G
Journal
Shock - Page No 291 (Fri Feb 01 00:00:00 UTC 2008)
Volume (Year)
29 (2008)
Product Usage
-
Soleus, plantaris and gastrocnemius VEGF mRNA responses to hypoxia and exercise are preserved in aged compared with young female C57BL/6 mice.
Authors
Gavin TP, Westerkamp LM, Zwetsloot KA
Journal
Acta Physiol (Oxf) - Page No 113 (Sun Oct 01 00:00:00 UTC 2006)
Volume (Year)
188 (2006)
Product Usage
-
VEGFR-3/Flt-4 mediates proliferation and chemotaxis in glial precursor cells.
Authors
Kranich S, Hattermann K, Specht A, Lucius R, Mentlein R
Journal
Neurochem Int - Page No 747 (Tue Dec 01 00:00:00 UTC 2009)
Volume (Year)
55 (2009)
Product Usage
-
Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice.
Authors
Kubota Y, Hirashima M, Kishi K, Stewart CL, Suda T
Journal
J Clin Invest - Page No 2393 (Tue Jul 01 00:00:00 UTC 2008)
Volume (Year)
118 (2008)
Product Usage
-
Fibroblast growth factor expression during skeletal fracture healing in mice.
Authors
Schmid GJ, Kobayashi C, Sandell LJ, Ornitz DM
Journal
Dev Dyn - Page No 766 (Sun Mar 01 00:00:00 UTC 2009)
Volume (Year)
238 (2009)
Product Usage
-
Parathyroid hormone-related protein interacts with vascular endothelial growth factor to promote fibrogenesis in the obstructed mouse kidney.
Authors
Ardura JA, Berruguete R, Ramila D, Alvarez-Arroyo MV, Esbrit P
Journal
Am J Physiol Renal Physiol - Page No F415 (Fri Aug 01 00:00:00 UTC 2008)
Volume (Year)
295 (2008)
Product Usage
-
Topical delivery of silver nanoparticles promotes wound healing.
Authors
Tian J, Wong KK, Ho CM, Lok CN, Yu WY, Che CM, Chiu JF, Tam PK
Journal
Chemmedchem - Page No 129 (Mon Jan 01 00:00:00 UTC 2007)
Volume (Year)
2 (2007)
Product Usage
-
Regulation of angiopoietin expression by bacterial lipopolysaccharide.
Authors
Mofarrahi M, Nouh T, Qureshi S, Guillot L, Mayaki D, Hussain SN
Journal
Am J Physiol Lung Cell Mol Physiol - Page No L955 (Thu May 01 00:00:00 UTC 2008)
Volume (Year)
294 (2008)
Product Usage
-
Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin.
Authors
Vihanto MM, Plock J, Erni D, Frey BM, Frey FJ, Huynh-Do U
Journal
Faseb J - Page No 1689 (Sat Oct 01 00:00:00 UTC 2005)
Volume (Year)
19 (2005)
Product Usage
-
Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice.
Authors
Murata N, Takashima Y, Toyoshima K, Yamamoto M, Okada H
Journal
J Control Release - Page No 246 (Thu Mar 20 00:00:00 UTC 2008)
Volume (Year)
126 (2008)
Product Usage
-
von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina.
Authors
Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H
Journal
Development - Page No 1563 (Sat May 01 00:00:00 UTC 2010)
Volume (Year)
137 (2010)
Product Usage
-
Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue.
Authors
Yin J, Gao Z, He Q, Zhou D, Guo Z, Ye J
Journal
Am J Physiol Endocrinol Metab - Page No E333 (Sun Feb 01 00:00:00 UTC 2009)
Volume (Year)
296 (2009)
Product Usage
-
IFATS collection: Fibroblast growth factor-2-induced hepatocyte growth factor secretion by adipose-derived stromal cells inhibits postinjury fibrogenesis through a c-Jun N-terminal kinase-dependent mechanism.
Authors
Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, Nishimura S, Manabe I, Gonda K, Yoshimura K
Journal
Stem Cells - Page No 238 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
27 (2009)
Product Usage
-
CD147 impacts angiogenesis and metastasis formation.
Authors
Voigt H, Vetter-Kauczok CS, Schrama D, Hofmann UB, Becker JC, Houben R
Journal
Cancer Invest - Page No 329 (Sun Mar 01 00:00:00 UTC 2009)
Volume (Year)
27 (2009)
Product Usage
-
Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity.
Authors
Pang C, Gao Z, Yin J, Zhang J, Jia W, Ye J
Journal
Am J Physiol Endocrinol Metab - Page No E313 (Fri Aug 01 00:00:00 UTC 2008)
Volume (Year)
295 (2008)
Product Usage
-
Critical role for osteopontin in diabetic nephropathy.
Authors
Nicholas SB, Liu J, Kim J, Ren Y, Collins AR, Nguyen L, Hsueh WA
Journal
Kidney Int - Page No 588 (Thu Apr 01 00:00:00 UTC 2010)
Volume (Year)
77 (2010)
Product Usage
-
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.
Authors
Pietras K, Pahler J, Bergers G, Hanahan D
Journal
Plos Med - Page No e19 (Tue Jan 29 00:00:00 UTC 2008)
Volume (Year)
5 (2008)
Product Usage
-
Simvastatin enhances VEGF production and ameliorates impaired wound healing in experimental diabetes.
Authors
Bitto A, Minutoli L, Altavilla D, Polito F, Fiumara T, Marini H, Galeano M, Calo M, Lo Cascio P, Bonaiuto M, Migliorato A, Caputi AP, Squadrito F
Journal
Pharmacol Res - Page No 159 (Fri Feb 01 00:00:00 UTC 2008)
Volume (Year)
57 (2008)
Product Usage
-
Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy.
Authors
Turunen MP, Lehtola T, Heinonen SE, Assefa GS, Korpisalo P, Girnary R, Glass CK, Vaisanen S, Yla-Herttuala S
Journal
Circ Res - Page No 604 (Fri Sep 11 00:00:00 UTC 2009)
Volume (Year)
105 (2009)
Product Usage
-
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice.
Authors
Granger A, Abdullah I, Huebner F, Stout A, Wang T, Huebner T, Epstein JA, Gruber PJ
Journal
Faseb J - Page No 3549 (Wed Oct 01 00:00:00 UTC 2008)
Volume (Year)
22 (2008)
Product Usage
-
Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis.
Authors
Wang IC, Meliton L, Ren X, Zhang Y, Balli D, Snyder J, Whitsett JA, Kalinichenko VV, Kalin TV
Journal
Plos One - Page No e6609 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
4 (2009)
Product Usage
-
Sema3a maintains normal heart rhythm through sympathetic innervation patterning.
Authors
Ieda M, Kanazawa H, Kimura K, Hattori F, Ieda Y, Taniguchi M, Lee JK, Matsumura K, Tomita Y, Miyoshi S, Shimoda K, Makino S, Sano M, Kodama I, Ogawa S, Fukuda K
Journal
Nat Med - Page No 604 (Tue May 01 00:00:00 UTC 2007)
Volume (Year)
13 (2007)
Product Usage
-

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