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See other TOP2A GE Assays ›
Gene Symbol:
TOP2A
Gene Name:
topoisomerase (DNA) II alpha
Gene Aliases:
TOP2, TP2A
Chromosome Location:
Chr.17: 40388521 - 40417950 on Build GRCh38
Species:
Human
Species Specific ID (Flybase ID):
-
Assay ID Hs06627146_s1
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Availability Made To Order
Catalog # 4351372
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  • Genomic Map
  • Assay Details
  • More Information

Genomic Map

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Assay Details

Gene Symbol: TOP2A
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_001067.3 NP_001058.2 1 141 70
XM_011525165.1 XP_011523467.1 1 87 70
GenBank mRNA BC013429.1 - 1 108 70
DB069825.1 - 1 141 70

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More Information


Additional Information:

This assay is in the 5'UTR region of the NM_001067.3, XM_011525165.1 transcripts.

Set Membership:

Ambion siRNA available Amplicon length less than or equal to 70 Mammalian Gene Collection Detect Genomic DNA Homo sapiens Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TOP2A

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Function(s) Process(es)

resolution of meiotic recombination intermediates
sister chromatid segregation
hematopoietic progenitor cell differentiation
DNA topological change
DNA ligation
DNA unwinding involved in DNA replication
mitotic recombination
cellular response to DNA damage stimulus
chromosome segregation
protein sumoylation
apoptotic chromosome condensation
embryonic cleavage
regulation of circadian rhythm
positive regulation of apoptotic process
mitotic DNA integrity checkpoint
positive regulation of viral genome replication
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
poly(A) RNA binding
protein heterodimerization activity

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