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See other IFNG GE Assays ›
Gene Symbol:
IFNG
Gene Name:
interferon gamma
Gene Aliases:
IFG, IFI
Chromosome Location:
Chr.12: 68154770 - 68159741 on Build GRCh38
Species:
Human
Species Specific ID (Flybase ID):
-
Assay ID Hs00174143_m1
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Catalog # 4331182
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  • Genomic Map
  • Assay Details
  • More Information
  • Citations (31)

Genomic Map

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Assay Details

Gene Symbol: IFNG
Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
RefSeq NM_000619.2 NP_000610.2 1 - 2 246 79
GenBank mRNA AB451324.1 - 1 - 2 120 79
AB451453.1 - 1 - 2 120 79
AF506749.1 - 1 - 2 54 79
AM903379.1 - 1 - 2 133 79
AY044154.1 - 1 - 2 51 79
AY255837.1 - 1 - 2 120 79
AY255839.1 - 1 - 2 54 79
BC070256.1 - 1 - 2 248 30414644 79
V00543.1 - 1 - 2 211 79
X13274.1 - 1 - 2 228 79
X87308.1 - 1 - 2 60 79

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More Information


Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1200011177.hg.1
This assay targets the same location as HTA transcript cluster(s) TC12001696.hg.1

Set Membership:

Ambion siRNA available Amplicon length between 71 and 85 Apoptosis Immune Tolerance Network Mammalian Gene Collection Homo sapiens Human Androgen Panel Human Chemokine Panel Human TGFB Panel Human Immune Response Human Alzheimer's Disease Human Diabetes Human Angiogenesis Inventoried Human_Immune Human_Angiogenesis Human_Androgen Human_Diabetes Human_Chemokine Human_TGFB Human_Alzheimer Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene IFNG

Panther Classification:

Molecular Function -

cytokine interferon superfamily intercellular signal molecule

Gene Ontology Categories:

Function(s) Process(es)

protein import into nucleus, translocation
negative regulation of transcription from RNA polymerase II promoter
neutrophil apoptotic process
regulation of the force of heart contraction
adaptive immune response
CD8-positive, alpha-beta T cell differentiation involved in immune response
apoptotic process
movement of cell or subcellular component
humoral immune response
cell cycle arrest
cell surface receptor signaling pathway
positive regulation of cell proliferation
response to virus
positive regulation of autophagy
positive regulation of gene expression
negative regulation of gene expression
positive regulation of epithelial cell migration
antigen processing and presentation
neutrophil chemotaxis
negative regulation of epithelial cell differentiation
endoplasmic reticulum unfolded protein response
negative regulation of myelination
positive regulation of synaptic transmission, cholinergic
negative regulation of interleukin-17 production
positive regulation of interleukin-12 production
positive regulation of interleukin-23 production
positive regulation of tumor necrosis factor production
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
positive regulation of peptidyl-serine phosphorylation of STAT protein
positive regulation of smooth muscle cell apoptotic process
positive regulation of T cell proliferation
response to drug
positive regulation of tyrosine phosphorylation of Stat1 protein
defense response to bacterium
defense response to protozoan
negative regulation of growth of symbiont in host
positive regulation of chemokine biosynthetic process
positive regulation of interleukin-12 biosynthetic process
positive regulation of MHC class II biosynthetic process
positive regulation of interleukin-6 biosynthetic process
positive regulation of nitric oxide biosynthetic process
positive regulation of neuron differentiation
positive regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of isotype switching to IgG isotypes
negative regulation of smooth muscle cell proliferation
positive regulation of interleukin-1 beta secretion
regulation of insulin secretion
T cell receptor signaling pathway
sensory perception of mechanical stimulus
positive regulation of membrane protein ectodomain proteolysis
defense response to virus
positive regulation of killing of cells of other organism
interferon-gamma-mediated signaling pathway
regulation of interferon-gamma-mediated signaling pathway
positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
positive regulation of fructose 1,6-bisphosphate metabolic process
positive regulation of vitamin D biosynthetic process
positive regulation of calcidiol 1-monooxygenase activity
cellular response to lipopolysaccharide
cellular response to interleukin-18
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway
regulation of neuronal action potential
positive regulation of exosomal secretion
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
regulation of hepatocyte proliferation
cytokine activity
interferon-gamma receptor binding

MicroArray Probes:

Affymetrix

Array Name Probe IDs Targets Target Type
Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 TC12001696.hg.1 HTA TC
Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 TC12001696.hg.1 HTA TC
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186694.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186694.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186694.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186694.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186694.hg.1 TC1200011177.hg.1 Clariom D TC
Affymetrix Human Clariom D Assay PSR1200186693.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186693.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186693.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186693.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186693.hg.1 TC1200011177.hg.1 Clariom D TC
Affymetrix Human Clariom D Assay PSR1200186690.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186690.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186690.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186690.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186690.hg.1 TC1200011177.hg.1 Clariom D TC
Affymetrix Human Clariom D Assay PSR1200186692.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186692.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186692.hg.1 ENST00000229135.3 Ensembl
Affymetrix Human Clariom D Assay PSR1200186692.hg.1 NM_000619.2 Refseq
Affymetrix Human Clariom D Assay PSR1200186692.hg.1 TC1200011177.hg.1 Clariom D TC

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Citations (31)

The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.
Authors
Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
Journal
Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 UTC 2009)
Volume (Year)
52 (2009)
Product Usage
-
Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin.
Authors
Johansen C, Usher PA, Kjellerup RB, Lundsgaard D, Iversen L, Kragballe K
Journal
Br J Dermatol - Page No 319 (Sun Feb 01 00:00:00 UTC 2009)
Volume (Year)
160 (2009)
Product Usage
-
Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells.
Authors
Evans KN, Nguyen L, Chan J, Innes BA, Bulmer JN, Kilby MD, Hewison M
Journal
Biol Reprod - Page No 816 (Fri Dec 01 00:00:00 UTC 2006)
Volume (Year)
75 (2006)
Product Usage
-
Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection.
Authors
Hueso M, Navarro E, Moreso F, O'Valle F, Perez-Riba M, Del Moral RG, Grinyo JM, Seron D
Journal
Am J Pathol - Page No 1696 (Thu Apr 01 00:00:00 UTC 2010)
Volume (Year)
176 (2010)
Product Usage
-
Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome.
Authors
Chetaille B, Bertucci F, Finetti P, Esterni B, Stamatoullas A, Picquenot JM, Copin MC, Morschhauser F, Casasnovas O, Petrella T, Molina T, Vekhoff A, Feugier P, Bouabdallah R, Birnbaum D, Olive D, Xerri L
Journal
Blood - Page No 2765 (Thu Mar 19 00:00:00 UTC 2009)
Volume (Year)
113 (2009)
Product Usage
-
Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells.
Authors
Ito T, Kanzler H, Duramad O, Cao W, Liu YJ
Journal
Blood - Page No 2423 (Wed Mar 15 00:00:00 UTC 2006)
Volume (Year)
107 (2006)
Product Usage
-
Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
Authors
Tadokera R, Meintjes G, Skolimowska KH, Wilkinson KA, Matthews K, Seldon R, Chegou NN, Maartens G, Rangaka MX, Rebe K, Walzl G, Wilkinson RJ
Journal
Eur Respir J - Page No (Fri Sep 03 00:00:00 UTC 2010)
Volume (Year)
 (2010)
Product Usage
-
Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.
Authors
Quekenborn-Trinquet V, Fogel P, Aldana-Jammayrac O, Ancian P, Demarchez M, Rossio P, Richards HL, Kirby B, Nguyen C, Voegel JJ, Griffiths CE
Journal
Br J Dermatol - Page No 489 (Tue Mar 01 00:00:00 UTC 2005)
Volume (Year)
152 (2005)
Product Usage
-
IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma.
Authors
Frederiksen KS, Lundsgaard D, Freeman JA, Hughes SD, Holm TL, Skrumsager BK, Petri A, Hansen LT, McArthur GA, Davis ID, Skak K
Journal
Cancer Immunol Immunother - Page No 1439 (Wed Oct 01 00:00:00 UTC 2008)
Volume (Year)
57 (2008)
Product Usage
-
Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.
Authors
Idali F, Wahlstrom J, Dahlberg B, Khademi M, Olsson T, Eklund A, Grunewald J
Journal
Respir Res - Page No 42 (Thu Jan 01 00:00:00 UTC 2009)
Volume (Year)
10 (2009)
Product Usage
-
Evasion of the mucosal innate immune system by herpes simplex virus type 2.
Authors
Peng T, Zhu J, Klock A, Phasouk K, Huang ML, Koelle DM, Wald A, Corey L
Journal
J Virol - Page No 12559 (Tue Dec 01 00:00:00 UTC 2009)
Volume (Year)
83 (2009)
Product Usage
-
Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma.
Authors
Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathe E, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC
Journal
Clin Cancer Res - Page No (Mon Oct 25 00:00:00 UTC 2010)
Volume (Year)
 (2010)
Product Usage
-
Comparing microarray versus RT-PCR assessment of renal allograft biopsies: similar performance despite different dynamic ranges.
Authors
Allanach K, Mengel M, Einecke G, Sis B, Hidalgo LG, Mueller T, Halloran PF
Journal
Am J Transplant - Page No 1006 (Thu May 01 00:00:00 UTC 2008)
Volume (Year)
8 (2008)
Product Usage
-
New means to monitor the effect of glucocorticoid therapy in children.
Authors
Rintamaki H, Salo HM, Vaarala O, Kolho KL
Journal
World J Gastroenterol - Page No 1104 (Sun Mar 07 00:00:00 UTC 2010)
Volume (Year)
16 (2010)
Product Usage
-
T helper 2 biased de novo immune response to Keyhole Limpet Hemocyanin in humans.
Authors
Spazierer D, Skvara H, Dawid M, Fallahi N, Gruber K, Rose K, Lloyd P, Heuerding S, Stingl G, Jung T
Journal
Clin Exp Allergy - Page No 999 (Wed Jul 01 00:00:00 UTC 2009)
Volume (Year)
39 (2009)
Product Usage
-
Prospective monitoring of tumor necrosis factor alpha and interferon gamma to predict the onset of acute and chronic graft-versus-host disease after allogeneic stem cell transplantation.
Authors
Ritchie D, Seconi J, Wood C, Walton J, Watt V
Journal
Biol Blood Marrow Transplant - Page No 706 (Thu Sep 01 00:00:00 UTC 2005)
Volume (Year)
11 (2005)
Product Usage
-
Regulation of the tonsil cytokine milieu favors HIV susceptibility.
Authors
Moutsopoulos NM, Vazquez N, Greenwell-Wild T, Ecevit I, Horn J, Orenstein J, Wahl SM
Journal
J Leukoc Biol - Page No 1145 (Wed Nov 01 00:00:00 UTC 2006)
Volume (Year)
80 (2006)
Product Usage
-
Anti-CD25 treatment and FOXP3-positive regulatory T cells in heart transplantation.
Authors
Vlad G, Ho EK, Vasilescu ER, Fan J, Liu Z, Cai JW, Jin Z, Burke E, Deng M, Cadeiras M, Cortesini R, Itescu S, Marboe C, Mancini D, Suciu-Foca N
Journal
Transpl Immunol - Page No 13 (Sun Jul 01 00:00:00 UTC 2007)
Volume (Year)
18 (2007)
Product Usage
-
Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.
Authors
Sandig H, McDonald J, Gilmour J, Arno M, Lee TH, Cousins DJ
Journal
Proc Natl Acad Sci U S A - Page No 12440 (Tue Jul 24 00:00:00 UTC 2007)
Volume (Year)
104 (2007)
Product Usage
-
Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions.
Authors
Simon D, Lindberg RL, Kozlowski E, Braathen LR, Simon HU
Journal
Exp Dermatol - Page No 441 (Thu Jun 01 00:00:00 UTC 2006)
Volume (Year)
15 (2006)
Product Usage
-
Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.
Authors
Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, D'Agati VD, Thaker HM, Remotti H, Galluzzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R
Journal
J Immunol - Page No 7432 (Fri Jun 01 00:00:00 UTC 2007)
Volume (Year)
178 (2007)
Product Usage
-
Postmenopausal expression changes of immune system-related genes in human bone tissue.
Authors
Kosa JP, Balla B, Kiss J, Podani J, Takacs I, Lazary A, Nagy Z, Bacsi K, Karsai A, Speer G, Lakatos P
Journal
J Clin Immunol - Page No 761 (Sun Nov 01 00:00:00 UTC 2009)
Volume (Year)
29 (2009)
Product Usage
-
Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.
Authors
Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T
Journal
J Immunol - Page No 1724 (Sat Aug 01 00:00:00 UTC 2009)
Volume (Year)
183 (2009)
Product Usage
-
Characterization of the innate immune signalling pathways in hepatocyte cell lines.
Authors
Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P
Journal
J Viral Hepat - Page No 888 (Mon Dec 01 00:00:00 UTC 2008)
Volume (Year)
15 (2008)
Product Usage
-
Interferon-gamma expression is an independent prognostic factor in ovarian cancer.
Authors
Marth C, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Doppler W, Daxenbichler G
Journal
Am J Obstet Gynecol - Page No 1598 (Mon Nov 01 00:00:00 UTC 2004)
Volume (Year)
191 (2004)
Product Usage
-
Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists.
Authors
Kamgang RK, Ramos I, Rodrigues Duarte L, Ghielmetti M, Freudenberg M, Dahinden C, Padovan E
Journal
Med Microbiol Immunol - Page No 369 (Mon Dec 01 00:00:00 UTC 2008)
Volume (Year)
197 (2008)
Product Usage
-
Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators.
Authors
Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengenes C, Lafontan M, Galitzky J, Bouloumie A
Journal
Arterioscler Thromb Vasc Biol - Page No 1608 (Thu Oct 01 00:00:00 UTC 2009)
Volume (Year)
29 (2009)
Product Usage
-
The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.
Authors
Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Gastl G, Gunsilius E, Marth C
Journal
Clin Cancer Res - Page No 8326 (Thu Dec 01 00:00:00 UTC 2005)
Volume (Year)
11 (2005)
Product Usage
-
Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.
Authors
Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM
Journal
Clin Exp Immunol - Page No 479 (Mon Jun 01 00:00:00 UTC 2009)
Volume (Year)
156 (2009)
Product Usage
-
Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.
Authors
Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA
Journal
Influenza Other Respi Viruses - Page No 139 (Sun Jul 01 00:00:00 UTC 2007)
Volume (Year)
1 (2007)
Product Usage
-
Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes.
Authors
Cruz AR, Moore MW, La Vake CJ, Eggers CH, Salazar JC, Radolf JD
Journal
Infect Immun - Page No 56 (Tue Jan 01 00:00:00 UTC 2008)
Volume (Year)
76 (2008)
Product Usage
-

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