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Invitrogen
Bcl-10 Monoclonal Antibody (151)
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FIGURE: 1 / 1
Bcl-10 Antibody (MA1-20160) in WB
Product Details
MA1-20160
Host/Isotype
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Conjugate
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Product Specific Information
MA1-20160 detects Bcl10 in human samples.
MA1-20160 has been successfully used in ELISA, immunohistochemistry (paraffin) and Western blot procedures.
The MA1-20160 immunogen is recombinant, full length, human Bcl10 protein.
Target Information
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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