ゲノム編集に関する研究論文

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TALs

• Liu, W et al. (2013) Synthetic TAL effectors for targeted enhancement of transgene expression in plants. Plant Biotechnology Journal (2013), pp. 1–11.
• Fu Y, et al. (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nature Biotechnology Jun 23.
• Boch J, et al. (2009) Breaking the code of DNA binding specificity of TAL-type III effectors. Science Dec 11;326(5959):1509-12.
• Moscou M, et al. (2009) A simple cipher governs DNA recognition by TAL effectors Science, Dec 11;326(5959):1501
• Miller J, et al. (2010) A TALE nuclease architecture for efficient genome editing. Nat. Biotech. Online pub.
• Morbitzer R, et al. (2011) Assembly of custom TALE-type DNA binding domains by modular cloning. Nucleic Acids Research, 1–10
• Hockemeyer D, et al. Genetic engineering of human pluripotent cells using TALE nucleases. (2011) Nat. Biotech. Online pub.
• Geibler R, et al. (2011) Transcriptional Activators of Human Genes with Programmable DNA-Specificity. PLoS ONE 6(5): e19509.
• Cermak T, et al. (2011) Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Research, 2011, 1–11
• Zhang F, et al. (2011) Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription Gene editing in mammalian cells. Nat. Biotech. 29(2) 149-154

siRNA

• Samuel A. Hasson et al (2013) High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy, Nature 504, 291–295
  
• Vinod Udayar et al, (2013) A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production, Cell Reports, Volume 5, Issue 6, Pages 1552-1563
  
• Virginie Buggia-Prévot et al (2013) A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production, Cell Reports, Volume 5, Issue 6, Pages 1536-1551
• Blattmann P¹, Schuberth C, Pepperkok R, Runz H.(2013) RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function, PLoS Genet. 2013;9(2)
• Pau G, Walter T, Neumann B, Hériché JK, Ellenberg J, Huber W1 (2013)
  Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay. BMC Bioinformatics. 2013 Oct 16;14:308
• Almaça J1, Faria D, Sousa M, Uliyakina I, Conrad C, Sirianant L, Clarke LA, Martins JP, Santos M, Heriché JK, Huber W, Schreiber R, Pepperkok R,Kunzelmann K, Amaral MD. (2013) High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets. Cell. 2013 Sep 12;154(6):1390-400
• Szymborska A1, de Marco A, Daigle N, Cordes VC, Briggs JA, Ellenberg J. (2013)
  Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging Science. 2013 Aug 9;341(6146):655-8
• Stadler C, Hjelmare M, Neumann B, Jonasson K, Pepperkok R, Uhlén M, Lundberg E (2012) Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. Journal of Proteomics 75(7):2236-2251
• Casanova CM1, Sehr P, Putzker K, Hentze MW, Neumann B, Duncan KE, Thoma C. (2012)
  Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation. PLoS One. 2012;7(9)
• Chrissie Y. Lee, Ronald L. Johnson, Jennifer Wichterman-Kouznetsova, Rajarshi Guha, Marc Ferrer,
  Pinar Tuzmen, Scott E. Martin, Wenge Zhu, Melvin L. DePamphilis (2012) High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them Methods 57 (2): 234-248
• Bo Rafn, Christian Friberg Nielsen, Sofie Hagel Andersen, Piotr Szyniarowski, Elisabeth Corcelle-Termeau, Erkka Valo, Nicole Fehrenbacher, Charlotta Johanne Olsen, Mads Daugaard, Christina Egebjerg, Trine Bøttzauw, Pekka Kohonen, Jesper Nylandsted, Sampsa Hautaniemi, Jose´ Moreira, Marja Jaattela, and Tuula Kallunki (2012) ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression Molecular Cell 45, 764–776
• Alexander V Sirotkin, Dmitriy Ovcharenko, and Milos Mlyncek (2010)
  Identification of protein kinases that control ovarian hormone release by selective siRNAs Journal of Molecular Endocrinology 44, 45–53.
• Thomas Horn, Thomas Sandmann, and Michael Boutros (2010)
  Design and evaluation of genome-wide libraries for RNA interference screens Genome Biology, 11:R61

Jump-In™ テクノロジー

• Clarke RJ and Apell HJ (1989) A stopped-flow kinetic study of the interaction of potential-sensitive oxonol dyes with lipid vesicles, Biophys Chem. Nov; 34(3):225-37.
• Kentish JC et al (1990) Calcium release from cardiac sarcoplasmic reticulum induced by photorelease of calcium or Ins(1,4,5)P3, Am J Physiol. Feb;258(2 Pt 2):H610-5.

Flp-In™ テクノロジー

All the references here

植物ゲノム 編集

• Imad Ajjawi et al (2010) Large-Scale Reverse Genetics in Arabidopsis: Case Studies from the Chloroplast 2010 Project, Plant Physiology February vol. 152 no. 2 529-540
• James W. Allen and Yair Shachar-Hill (2009) Sulfur Transfer through an Arbuscular Mycorrhiza, Plant Physiology January vol. 149 no. 1 549-560