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Invitrogen
mGluR2/mGluR3 Polyclonal Antibody
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Product Details
PA5-99485
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Antibody detects endogenous levels of total GluR2/3.
Target Information
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member C; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; glutamate receptor, metabotropic 3; M mGlu3; Metabotropic glutamate receptor 2; Metabotropic glutamate receptor 3; mGluR2; mGluR3
Gene Aliases: 0710001G23Rik; 4930441L02Rik; GLUR2; GLUR3; GPRC1B; GPRC1C; GRM2; GRM3; mGlu2; mGlu3; MGLUR2; MGLUR3; mGluR7
UniProt ID: (Human) Q14416, (Human) Q14832, (Mouse) Q14BI2, (Rat) P31421, (Mouse) Q9QYS2, (Rat) P31422
Entrez Gene ID: (Human) 2912, (Human) 2913, (Mouse) 108068, (Rat) 24415, (Mouse) 108069, (Rat) 24416
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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