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  • Primary Antibodies ›
  • cIAP2 Antibodies

Invitrogen

cIAP2 Polyclonal Antibody

View all (34) cIAP2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite cIAP2 Polyclonal Antibody

  • Antibody Testing Data (2)
cIAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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cIAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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cIAP2 Antibody (PA5-142614) in IHC (P)

Immunohistochemistry analysis of cIAP2 in human tonsil. Samples were incubated with cIAP2 polyclonal antibody (Product # PA5-142614) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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cIAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
cIAP2 Antibody in Western Blot (WB)
cIAP2 Polyclonal Antibody

Product Details

PA5-142614

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.3 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence C-SQPTFPSSVT.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2933260

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Target Information

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AIP 2; API2; Apoptosis inhibitor 2; baculoviral IAP repeat-containing 3; Baculoviral IAP repeat-containing protein 3; C-IAP2; Cellular inhibitor of apoptosis 2; H HIAP1; H MALT2; hIAP-1; IAP homolog; IAP homolog C; IAP-1; Inhibitor of apoptosis protein 1; mammalian IAP homolog C; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1

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Gene Aliases: AIP1; API2; BIRC3; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49

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UniProt ID: (Human) Q13489

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Entrez Gene ID: (Human) 330

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Function(s)
ubiquitin-protein transferase activity protein binding zinc ion binding transferase activity ligase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Process(es)
apoptotic process cell surface receptor signaling pathway I-kappaB kinase/NF-kappaB signaling spermatogenesis regulation of tumor necrosis factor-mediated signaling pathway regulation of necrotic cell death protein ubiquitination positive regulation of protein ubiquitination tumor necrosis factor-mediated signaling pathway regulation of toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway NIK/NF-kappaB signaling regulation of RIG-I signaling pathway regulation of apoptotic process negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling regulation of innate immune response regulation of inflammatory response protein heterooligomerization regulation of necroptotic process negative regulation of necroptotic process regulation of nucleotide-binding oligomerization domain containing signaling pathway mitotic spindle assembly inhibition of cysteine-type endopeptidase activity involved in apoptotic process regulation of cysteine-type endopeptidase activity
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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