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Invitrogen
beta Actin Loading Control Monoclonal Antibody (BA3R), DyLight™ 800 4X PEG
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FIGURE: 1 / 14
beta Actin Loading Control Antibody (MA5-15739-D800) in ICC/IF
Product Details
MA5-15739-D800
Species Reactivity
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Product Specific Information
MA5-15739-D800 has been successfully used for Western blotting and immunofluorescence. DyLight 800 4X PEG has an excitation/emission of 783/797 nm. For visualization of actin filaments by immunofluorescence, fixation and permeabilization with methanol is required.
Target Information
Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin, beta; Actin, cytoplasmic 1; beta cytoskeletal actin; Beta-actin; cytoplasmic 1; cytoplasmic beta-actin; gamma non-muscle actin; PS1TP5-binding protein 1
Gene Aliases: ACT-5; ACTB; actin; Actx; Bact; beta-actin; BRWS1; E430023M04Rik; PS1TP5BP1; RCJMB04_4h19
UniProt ID: (Rabbit) P29751, (Human) P60709, (Chicken) P60706, (Rat) P60711, (Mouse) P60710
Entrez Gene ID: (Rabbit) 100009272, (Human) 60, (Chicken) 396526, (Rat) 81822, (Mouse) 11461
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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