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Invitrogen
alpha Adducin Polyclonal Antibody
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FIGURE: 1 / 1
alpha Adducin Antibody (PA5-90820) in WB
Product Details
PA5-90820
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Shipping conditions
RRID
Product Specific Information
Immunogen sequence: MILQSPAFCE ELESMIQEQF KKGKNPTGLL ALQQIADFMT TNVPNVYPAA PQGGMAALNM SLGMVTPVND LRGSDSIAYD KGEKLLRCKL AAFYRLADLF GWSQLIYNHI TTRVNSEQEH FLIVPFGLLY SEVTASSLVK INLQGDIVDR GSTNLGVNQA GFTLHSAIYA ARPDVKCVVH IHTPAGAAVS AMKCGLLPIS PEALSLGEVA YHDYHGILVD EEEKVLIQKN LGPKSKVLIL R; Positive Samples: BT-474, Mouse brain; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton
Target Information
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ADD2; ADDB; adducin 1 (alpha); Adducin beta; Adducin-1; Adducin-alpha; Adducin-beta; Adducin1; Alpha adducin; Alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha
Gene Aliases: ADD1; ADDA; AI256389
UniProt ID: (Human) P35611, (Mouse) Q9QYC0
Entrez Gene ID: (Human) 118, (Mouse) 11518
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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