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  • WNT5A Antibodies

Invitrogen

WNT5A Polyclonal Antibody

View all (19) WNT5A antibodies

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Datasheet
Protocols
Questions & Answers

Cite WNT5A Polyclonal Antibody

  • Antibody Testing Data (1)
WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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WNT5A Antibody (PA5-67629) in IHC (P)

Immunohistochemical analysis of WNT5A in paraffin-embedded Human tonsil tissue using (left) WNT5A Polyclonal Antibody (Product # PA5-67629) at a 1:25 dilution and (right) is treated with synthetic peptide. (Original magnification: x200). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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WNT5A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-67629

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:50
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthesized peptide derived from human WNT5A.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2688466

Product Specific Information

Predicted to react with Mouse and Rat samples.

Target Information

Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: OTTHUMP00000212837; OTTHUMP00000212861; Protein Wnt-5a; wingless-related MMTV integration site 5A; wingless-type MMTV integration site 5A; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein

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Gene Aliases: 8030457G12Rik; hWNT5A; Wnt-5a; WNT5A

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UniProt ID: (Human) P41221, (Mouse) P22725

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Entrez Gene ID: (Human) 7474, (Rat) 64566, (Mouse) 22418

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Function(s)
transcription factor activity, sequence-specific DNA binding frizzled binding frizzled-2 binding receptor tyrosine kinase-like orphan receptor binding cytokine activity protein binding protein domain specific binding transcription regulatory region DNA binding receptor agonist activity chemoattractant activity involved in axon guidance molecular_function receptor binding
Process(es)
activation of MAPK activity ameboidal-type cell migration establishment of planar polarity somitogenesis positive regulation of cytokine production epithelial to mesenchymal transition neural tube closure positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation heart looping morphogenesis of an epithelium positive regulation of mesenchymal cell proliferation positive regulation of cytokine secretion involved in immune response type B pancreatic cell development pericardium morphogenesis axis elongation protein phosphorylation Wnt signaling pathway, calcium modulating pathway JNK cascade activation of JUN kinase activity determination of left/right symmetry axon guidance hindgut morphogenesis midgut development positive regulation of cell proliferation male gonad development anterior/posterior axis specification, embryo anterior/posterior pattern specification response to organic substance positive regulation of endothelial cell migration positive regulation of peptidyl-threonine phosphorylation positive regulation of T cell chemotaxis positive regulation of neuron projection development response to organic cyclic compound Wnt signaling pathway cell migration olfactory bulb interneuron development neural tube development positive regulation of cell-cell adhesion cell differentiation neuron differentiation keratinocyte differentiation lung development embryonic limb morphogenesis negative regulation of BMP signaling pathway positive regulation of cGMP metabolic process prostate gland development activation of protein kinase B activity response to estradiol positive regulation of interferon-gamma production positive regulation of interleukin-6 production regulation of protein localization positive regulation of peptidyl-serine phosphorylation response to testosterone cellular protein localization limb morphogenesis non-canonical Wnt signaling pathway post-anal tail morphogenesis non-canonical Wnt signaling pathway via JNK cascade negative regulation of fibroblast growth factor receptor signaling pathway wound healing inner ear morphogenesis embryonic digit morphogenesis positive regulation of macrophage activation negative regulation of apoptotic process positive regulation of JUN kinase activity estrous cycle positive regulation of chemokine biosynthetic process cell fate commitment negative regulation of fat cell differentiation positive regulation of protein catabolic process positive regulation of angiogenesis positive regulation of ossification positive regulation of endocytosis positive regulation of meiotic nuclear division negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade development of primary male sexual characteristics positive regulation of fibroblast proliferation lung alveolus development digestive tract morphogenesis embryonic skeletal system development genitalia development neuron projection morphogenesis negative regulation of axon extension involved in axon guidance hypophysis morphogenesis positive regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive regulation of interleukin-1 beta secretion positive regulation of inflammatory response negative chemotaxis positive regulation of NF-kappaB transcription factor activity cartilage development response to glucocorticoid negative regulation of synapse assembly response to hyperoxia palate development convergent extension convergent extension involved in organogenesis uterus development cervix development vagina development canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway urinary bladder development face development positive regulation of type I interferon-mediated signaling pathway lateral sprouting involved in mammary gland duct morphogenesis tube closure mesenchymal-epithelial cell signaling negative regulation of prostatic bud formation mammary gland branching involved in thelarche epithelial cell proliferation involved in mammary gland duct elongation positive regulation of response to cytokine stimulus regulation of branching involved in mammary gland duct morphogenesis positive regulation of macrophage cytokine production positive regulation of cartilage development planar cell polarity pathway involved in outflow tract morphogenesis planar cell polarity pathway involved in ventricular septum morphogenesis planar cell polarity pathway involved in cardiac right atrium morphogenesis planar cell polarity pathway involved in cardiac muscle tissue morphogenesis planar cell polarity pathway involved in pericardium morphogenesis positive regulation of thymocyte apoptotic process cellular response to molecule of bacterial origin cellular response to lipopolysaccharide cellular response to calcium ion cellular response to interferon-gamma hematopoietic stem cell proliferation dopaminergic neuron differentiation cellular response to transforming growth factor beta stimulus negative regulation of mesenchymal cell proliferation primitive streak formation positive regulation of protein kinase C signaling negative regulation of canonical Wnt signaling pathway cochlea morphogenesis planar cell polarity pathway involved in neural tube closure positive regulation of cell-cell adhesion mediated by cadherin positive regulation of interleukin-8 secretion lens development in camera-type eye planar cell polarity pathway involved in axis elongation optic cup formation involved in camera-type eye development synapse assembly positive regulation of protein binding chemoattraction of serotonergic neuron axon chemorepulsion of dopaminergic neuron axon establishment of epithelial cell apical/basal polarity negative regulation of melanin biosynthetic process paraxial mesoderm formation notochord morphogenesis convergent extension involved in axis elongation planar cell polarity pathway involved in gastrula mediolateral intercalation mesodermal to mesenchymal transition involved in gastrulation cellular response to retinoic acid activation of GTPase activity melanocyte proliferation positive regulation of protein kinase C activity positive regulation of protein localization to synapse regulation of cellular protein localization excitatory synapse assembly inhibitory synapse assembly negative regulation of cell proliferation in midbrain Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation positive regulation of non-canonical Wnt signaling pathway signal transduction cell-cell signaling multicellular organism development embryo development organ morphogenesis
It has to be done as per old AB suggested Products section.
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