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  • Primary Antibodies ›
  • VDAC1/VDAC2 Antibodies

Proteintech

VDAC1/2 Polyclonal Antibody

137 References

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite VDAC1/2 Polyclonal Antibody

  • Antibody Testing Data (19)
VDAC1/2 Antibody in Immunocytochemistry (ICC/IF)
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VDAC1/2 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 19

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VDAC1/2 Antibody (10866-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 10866-1-AP (VDAC1/Porin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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VDAC1/2 Antibody in Immunocytochemistry (ICC/IF)
VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VDAC1/2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
VDAC1/2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Western Blot (WB)
VDAC1/2 Antibody in Immunoprecipitation (IP)
VDAC1/2 Polyclonal Antibody

Product Details

10866-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
View 119 publications 119 publications

Immunohistochemistry (IHC)

-
View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50
-

Immunocytochemistry (ICC/IF)

1:50-1:500
View 10 publications 10 publications

Immunoprecipitation (IP)

0.5-4.0 µg
View 4 publications 4 publications

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Insect, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

VDAC1/2 Fusion Protein Ag1144 (1-283 aa encoded by BC008482)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This polyclonal antibody raised against full-length human VDAC1 protein can cross react with VDAC2.

Immunogen sequence: MAVPPTYAD LGKSARDVFT KGYGFGLIKL DLKTKSENGL EFTSSGSANT ETTKVTGSLE TKYRWTEYGL TFTEKWNTDN TLGTEITVED QLARGLKLTF DSSFSPNTGK KNAKIKTGYK REHINLGCDM DFDIAGPSIR GALVLGYEGW LAGYQMNFET AKSRVTQSNF AVGYKTDEFQ LHTNVNDGTE FGGSIYQKVN KKLETAVNLA WTAGNSNTRF GIAAKYQIDP DACFSAKVNN SSLIGLGYTQ TLKPGIKLTL SALLDGKNVN AGGHKLGLGL EFQA (1-283 aa encoded by BC008482)

Target Information

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: B36-VDAC; mVDAC1; mVDAC5; Non-selective voltage-gated ion channel VDAC1; Non-selective voltage-gated ion channel VDAC2; Outer mitochondrial membrane protein porin 1; Outer mitochondrial membrane protein porin 2; Plasmalemmal porin; Porin 31HL; Porin 31HM; rVDAC1; VDAC-1; VDAC-2; VDAC-5; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 5; Voltage-dependent anion-selective channel protein 6

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Gene Aliases: AL033343; mVDAC2; mVDAC6; POR; PORIN; VDAC; VDAC-1; VDAC1; VDAC2; Vdac5; Vdac6

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UniProt ID: (Human) P21796, (Human) P45880, (Mouse) Q60932, (Rat) Q9Z2L0, (Mouse) Q60930, (Rat) P81155

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Entrez Gene ID: (Human) 7416, (Human) 7417, (Mouse) 22333, (Rat) 83529, (Mouse) 22334, (Rat) 83531

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Function(s)
protein binding voltage-gated anion channel activity porin activity protein kinase binding protein complex binding ion channel binding nucleotide binding anion channel activity
Process(es)
behavioral fear response transport ion transport anion transport mitochondrial calcium ion transport apoptotic process chemical synaptic transmission neuron-neuron synaptic transmission learning regulation of anion transport transmembrane transport anion transmembrane transport regulation of anion transmembrane transport negative regulation of protein polymerization negative regulation of intrinsic apoptotic signaling pathway epithelial cell differentiation ion transmembrane transport regulation of ion transmembrane transport viral process macroautophagy regulation of mitophagy negative regulation of reactive oxygen species metabolic process
It has to be done as per old AB suggested Products section.
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