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Invitrogen
VAV1 Monoclonal Antibody (GT557)
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FIGURE: 1 / 4
VAV1 Antibody (MA5-31488) in ICC/IF
Product Details
MA5-31488
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (92%), Rat (92%), Pig (96%), Bovine (96%).
Positive Control: Jurkat, NCI-H929.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: oncogene vav; p95vav; Proto-oncogene vav; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav oncogene; vav proto-oncogene
Gene Aliases: VAV; vav-T; VAV1
UniProt ID: (Human) P15498, (Mouse) P27870
Entrez Gene ID: (Human) 7409, (Mouse) 22324
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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