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Invitrogen
VASP Polyclonal Antibody
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FIGURE: 1 / 2
VASP Antibody (PA5-17769) in WB
Product Details
PA5-17769
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with VASP homologues, such as EVL and Mena.
Target Information
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Enah/Vasp-like; Vasodilator-stimulated phosphoprotein; VASP
Gene Aliases: VASP
UniProt ID: (Human) P50552, (Mouse) Q3TAP0
Entrez Gene ID: (Human) 7408, (Rat) 361517, (Mouse) 22323
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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