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Proteintech
UHRF1 Polyclonal Antibody
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Product Details
21402-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: QSLVLPHST KERDSELSDT DSGCCLGQSE SDKSSTHGEA AAETDSRPAD EDMWDETELG LYKVNEYVDA RDTNMGAWFE AQVVRVTRKA PSRDEPCSST SRPALEEDVI YHVKYDDYPE NGVVQMNSRD VRARARTIIK WQDLEVGQVV MLNYNPDNPK ERGFWYDAEI SRKRETRTAR ELYANVVLGD DSLNDCRIIF VDEVFKIERP GEGSPMVDNP MRRKSGPSCK HCKDDVNRLC RVCACHLCGG RQDPDKQLMC DECDMAFHIY CLDPPLSSVP SEDEWYCPEC RNDASEVVLA GERLRE (88-392 aa encoded by BC113875)
Target Information
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ac2-121; E3 ubiquitin-protein ligase UHRF1; FLJ21925; Hnp95 Huhrf1; hUHRF1; HuNp95; Inverted CCAAT box-binding protein of 90 kDa; MGC138707; nuclear phosphoprotein 95; Nuclear protein 95; Nuclear zinc finger protein Np95; RING finger protein 106; RING-type E3 ubiquitin transferase UHRF1; Transcription factor ICBP90; ub; Ubiquitin-like PHD and RING finger domain-containing protein 1; ubiquitin-like with PHD and ring finger domains 1; Ubiquitin-like-containing PHD and RING finger domains protein 1
Gene Aliases: hNP95; hUHRF1; huNp95; ICBP90; NP95; RNF106; TDRD22; UHRF1
UniProt ID: (Human) Q96T88
Entrez Gene ID: (Human) 29128
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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