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  • TUBA1A/TUBA1B Antibodies

Bioss

TUBA1A/TUBA1B Polyclonal Antibody, Cyanine3

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Datasheet
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Questions & Answers

Cite TUBA1A/TUBA1B Polyclonal Antibody, Cyanine3

TUBA1A/TUBA1B Polyclonal Antibody, Cyanine3

Product Details

BS-20496R-CY3

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-5,000
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human TUBA1A & TUBA1B (amino acids 401-451).
View immunogen

Conjugate

Cyanine3 Cyanine3 Cyanine3

Excitation/Emission Max

554/566 nm View spectra spectra

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alpha tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin ubiquitous; hum-a-tub1; hum-a-tub2; Talpha1 alpha-tubulin; TUBA1A; TUBA1B; Tubulin alpha-1 chain; Tubulin alpha-1A chain; Tubulin alpha-1B chain; Tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-ubiquitous chain; Tubulin B-alpha-1; Tubulin K-alpha-1; tubulin, alpha 1; tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 2; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous

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Gene Aliases: B-ALPHA-1; K-ALPHA-1; LIS3; RGD1565476; Tuba-1; Tuba1; TUBA1A; TUBA1B; Tuba2; TUBA3

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UniProt ID: (Human) Q71U36, (Human) P68363, (Mouse) P68369, (Rat) P68370, (Mouse) P05213, (Rat) Q6P9V9

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Entrez Gene ID: (Human) 7846, (Human) 10376, (Mouse) 22142, (Rat) 64158, (Mouse) 22143, (Rat) 500929

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Function(s)
GTPase activity structural molecule activity structural constituent of cytoskeleton protein binding GTP binding protein domain specific binding double-stranded RNA binding ubiquitin protein ligase binding nucleotide binding protein heterodimerization activity
Process(es)
microtubule-based process protein polymerization cellular response to interleukin-4 metabolic process microtubule cytoskeleton organization cytoskeleton-dependent intracellular transport cell division G2/M transition of mitotic cell cycle cytoskeleton organization
It has to be done as per old AB suggested Products section.
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