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  • TREM2 Antibodies

Invitrogen

TREM2 Monoclonal Antibody (78.18), FITC

2 References
View all (35) TREM2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TREM2 Monoclonal Antibody (78.18), FITC

  • Antibody Testing Data (1)
TREM2 Antibody in Flow Cytometry (Flow)
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TREM2 Antibody in Flow Cytometry (Flow)
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TREM2 Antibody (MA5-28223) in Flow

Flow cytometry of TREM2 in J774 cells. Sample was incubated with TREM2 monoclonal antibody (Product # MA5-28223) conjugated with FITC. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TREM2 Antibody in Flow Cytometry (Flow)

Product Details

MA5-28223

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

Assay-dependent
View 2 publications 2 publications
Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

78.18

Immunogen

Mouse TREM-2 Fc fusion protein

Conjugate

FITC FITC FITC
  • Unconjugated
  • Request custom conjugation

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 1% BSA

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2745193

Product Specific Information

Rat anti Mouse TREM-2 antibody, clone 78.18 recognizes triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily.

Target Information

TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Bioinformatics

Protein Aliases: OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; TREM-2; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c

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Gene Aliases: TREM-2; Trem2; Trem2a; Trem2b; Trem2c

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UniProt ID: (Mouse) Q99NH8

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Entrez Gene ID: (Mouse) 83433

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Function(s)
lipopolysaccharide binding transmembrane signaling receptor activity protein binding peptidoglycan binding lipoteichoic acid binding scaffold protein binding
Process(es)
positive regulation of antigen processing and presentation of peptide antigen via MHC class II signal transduction lipopolysaccharide-mediated signaling pathway detection of lipopolysaccharide detection of peptidoglycan innate immune response positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of ERK1 and ERK2 cascade detection of lipoteichoic acid cellular response to lipoteichoic acid cellular response to peptidoglycan dendritic cell differentiation positive regulation of protein localization to plasma membrane positive regulation of C-C chemokine receptor CCR7 signaling pathway positive regulation of CD40 signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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